SynthesisBMC pediatrics2016
Childhood asthma and physical activity: a systematic review with meta-analysis and Graphic Appraisal Tool for Epidemiology assessment.
Synthesis in BMC pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Vitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study.PLoS medicine · 2017Pooled it
- mApplied biochemistry and biotechnology · 2026Article
- Vitamin D and asthma in pediatrics: evidence and clinical implications.World journal of pediatrics : WJP · 2025Article
- Integrated strategies for type 2 diabetes prevention: The role of diet and exercise.AIMS public health · 2025Review
- Associations between leisure sedentary behaviors, physical activity, and chronic respiratory diseases: a Mendelian randomization study.Archives of medical science : AMS · 2025Article
- Asthma Inception: Epidemiologic Risk Factors and Natural History Across the Life Course.American journal of respiratory and critical care medicine · 2024Review
- Frequency of Severe Asthma and Its Clinical Phenotypes at the Asthma Clinic in One of the Largest Sudanese Tertiary Pediatric Hospitals: A Cross-Sectional Hospital-Outpatient-Based Study.Journal of asthma and allergy · 2024Article
- Current Approaches in the Multimodal Management of Asthma in Adolescents-From Pharmacology to Personalized Therapy.Biomedicines · 2023Review
- Environmental exposures in early-life and general health in childhood.Environmental health : a global access science source · 2023Article
- Asthma-related lung function and physical activity patterns among children living in urban neighborhoods.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023Article
- ERS International Congress 2022: highlights from the Paediatrics Assembly.ERJ open research · 2023Review
- Changes in physical activity and sedentary time among children with asthma during the COVID-19 pandemic and influencing factors.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023Article
- Article
- Effects of physical activity on lung function and quality of life in asthmatic children: An updated systematic review and meta-analysis.Frontiers in pediatrics · 2023Review
- Physical Activity Frequency and Health-Related Quality of Life in Spanish Children and Adolescents with Asthma: A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- Parental Education Moderates the Relation between Physical Activity, Dietary Patterns and Atopic Diseases in Adolescents.Children (Basel, Switzerland) · 2022Article
- Association between Land Use Mix and Respiratory Symptoms and Asthma in Children from the Generation XXI Birth Cohort.Journal of urban health : bulletin of the New York Academy of Medicine · 2022Article
- Self-Reported Physical Activity and Asthma Risk in Children.The journal of allergy and clinical immunology. In practice · 2022Article
- Asthma and Physical Activity in Urban Children.Journal of pediatric psychology · 2021Article
- Physical activity, lung function, and sleep outcomes in urban children with asthma.Pediatric pulmonology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChildhood asthma is a global problem affecting the respiratory health of children. Physical activity (PA) plays a role in the relationship between asthma and respiratory health. We hypothesized that a low level of PA would be associated with asthma in children and adolescents. The objectives of our study were to (1) summarize the evidence available on associations between PA and asthma prevalence in children and adolescents and (2) assess the role of PA in new-onset or incident asthma among children and adolescents.
methodsWe searched Medline, the Cochrane Library, and Embase and extracted data from original articles that met the inclusion criteria. Summary odds ratios (ORs) and confidence intervals (CIs) were used to express the results of the meta-analysis (forest plot). We explored heterogeneity using funnel plots and the Graphic Appraisal Tool for Epidemiology (GATE).
resultsWe retrieved 1,571 titles and selected 11 articles describing three cohort and eight cross-sectional studies for inclusion. A meta-analysis of the cohort studies revealed a risk of new-onset asthma in children with low PA (OR [95 % CI] 1.32 [0.95; 1.84] [random effects] and 1.35 [1.13; 1.62] [fixed effects]). Three cross-sectional studies identified significant positive associations between childhood asthma or asthma symptoms and low PA.
conclusionsChildren and adolescents with low PA levels had an increased risk of new-onset asthma, and some had a higher risk of current asthma/or wheezing; however, there was some heterogeneity among the studies. This review reveals a critical need for future longitudinal assessments of low PA, its mechanisms, and its implications for incident asthma in children. The systematic review was prospectively registered at PROSPERO (registration number: CRD42014013761; available at: http://www.crd.york.ac.uk/PROSPERO [accessed: 24 March 2016]).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.