ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2016
Implementation of Nationwide Real-time Whole-genome Sequencing to Enhance Listeriosis Outbreak Detection and Investigation.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
186 citing papers in PubMed, 1 synthesis or guideline pooled it.
- 2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Guideline
- Microbiological Hazards, Not Undeclared Allergens, Dominate United States Food Recalls: An Analysis of 24,761 Product Recall Records, 2013-2025.Foods (Basel, Switzerland) · 2026Article
- Listeriosis: a re-emerging threat to public health-a comprehensive review of its epidemiology, pathogenesis, and control measures.Infection · 2026Review
- Gut check: Exploring tools, techniques, and future directions in microbiome research.Poultry science · 2026Article
- Reoccurring, Emerging, and Persisting (REP) Strains: A Framework for Surveillance and Investigation of Pathogens of Public Health Importance.Journal of food protection · 2026Review
- Probing Genomic Diversity ofFoods (Basel, Switzerland) · 2026Article
- Genomic epidemiology ofProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Evaluating the use of whole-genome sequencing and SangerJournal of medical microbiology · 2026Article
- Whole genome sequencing in animal health: applications, challenges, and future directions.BMC veterinary research · 2026Review
- Epidemiology, antimicrobial resistance transmission, and One Health-based prevention of non-typhoidalFrontiers in microbiology · 2026Review
- Integrating epidemiology with genomic tracing to uncover concealed transmission networks in a brucellosis outbreak, Shandong, China.Frontiers in cellular and infection microbiology · 2026Article
- Genomics in Epidemiology and Disease Surveillance: An Exploratory Analysis.Life (Basel, Switzerland) · 2025Review
- Genomic analysis of Listeria monocytogenes diversity over a 10-year period in Uruguay.Scientific reports · 2025Article
- Retrospective Analysis of Historical Listeria monocytogenes Clinical Isolates, New York, USA, 2000-2021Emerging infectious diseases · 2025Review
- An Overview of Listeriosis Outbreak Investigations in the United States Linked to Imported Enoki Mushrooms and Associated Regulatory Activities, Research, and Food Safety Knowledge Gaps.Comprehensive reviews in food science and food safety · 2025Review
- Genomic epidemiology of aMicrobial genomics · 2025Article
- Advancing microbial risk assessment: perspectives from the evolution of detection technologies.NPJ science of food · 2025Review
- Validation of Core and Whole-Genome Multi-Locus Sequence Typing Schemes for Shiga-Toxin-ProducingMicroorganisms · 2025Article
- The impact of integrated genomic surveillance on non-typhoidalThe Lancet regional health. Western Pacific · 2025Article
- Compatibility of whole-genome sequencing data from Illumina and Ion Torrent technologies in genome comparison analysis ofMicrobial genomics · 2025Article
126 more citing papers are in PubMed but not listed here.
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32 authors.
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Abstract
Listeria monocytogenes (Lm) causes severe foodborne illness (listeriosis). Previous molecular subtyping methods, such as pulsed-field gel electrophoresis (PFGE), were critical in detecting outbreaks that led to food safety improvements and declining incidence, but PFGE provides limited genetic resolution. A multiagency collaboration began performing real-time, whole-genome sequencing (WGS) on all US Lm isolates from patients, food, and the environment in September 2013, posting sequencing data into a public repository. Compared with the year before the project began, WGS, combined with epidemiologic and product trace-back data, detected more listeriosis clusters and solved more outbreaks (2 outbreaks in pre-WGS year, 5 in WGS year 1, and 9 in year 2). Whole-genome multilocus sequence typing and single nucleotide polymorphism analyses provided equivalent phylogenetic relationships relevant to investigations; results were most useful when interpreted in context of epidemiological data. WGS has transformed listeriosis outbreak surveillance and is being implemented for other foodborne pathogens.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.