ArticleDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2016
[Klatskin tumor: long-term survival following surgery].
Article in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Perineural invasion of hilar cholangiocarcinoma in Chinese population: One center's experience.World journal of gastrointestinal oncology · 2020Article
- Article
- Long-term Survival after resection for perihilar cholangiocarcinoma: Impact of UICC staging and surgical procedure.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019Article
- [Intrahepatic cholangiocarcinoma : Results after 84 resections].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018Article
- Resection for Klatskin tumors: technical complexities and results.Translational gastroenterology and hepatology · 2018Review
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9 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPerihilar cholangiocarcinoma (Klatskin tumor) is a rare tumor entity with an unfavorable prognosis despite optimal treatment.
objectivesThe aim of the study is to investigate beneficial histopathological features and recommendations for surgery in perihilar cholangiocarcinoma to improve patients' long term survival. MATERIAL AND
methods192 patients suffering from perihilar cholangiocarcinoma underwent attempted tumor resection between 1998 and 2008 at our clinic. 50 patients survived more than 2 years. The follow-up ended in December 2013. The resection type, the UICC stage and histopathological features were compared between three groups (2-3-year, 3-5-year and > 5-year survival groups).
resultsThe overall 5‑year survival rate of the study groups was 32 %, and even 16 % survived more than 10 years after surgery. Patients with lymph node positive tumors (p = 0.0126) and distant metastasis (p = 0.0376) had the poorest survival rate. Perineural invasion had no significant impact on the overall survival, but patients surviving more than 5 years had the lowest incidence of perineural invasion with 18.75 %. Caudate lobectomy was significantly (p = 0.011) associated with a survival of more than 5 years in our study.
conclusionsComplete tumor resection with additional caudate lobe resection is associated with long-term survival. Perineural invasion seems to be a negative prognostic factor for long-term survival.
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