Evidence map›Paper›PMID 27089922›Full record

ReviewPediatric rheumatology online journal2016

Clinical outcome measures in juvenile idiopathic arthritis.

Alessandro Consolaro, Gabriella Giancane, Benedetta Schiappapietra, Sergio Davì, Serena Calandra, Stefano Lanni, Angelo Ravelli

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Pediatric rheumatology online journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05545098 (The Role of Musculoskeletal Ultrasound Versus Serum Survivin and Lubricin Levels in Evaluation of Disease Activity in Juvenile Idiopathic Arthritis), which is not on this map. Cited by 117 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 4 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05545098 unknown statusnot on this mapstarted 2022, after this paper: background citation

The Role of Musculoskeletal Ultrasound Versus Serum Survivin and Lubricin Levels in Evaluation of Disease Activity in Juvenile Idiopathic Arthritis

TypeobservationalSponsorAssiut UniversityRan2022 to 2024Enrolled106ConditionsJuvenile Idiopathic Arthritis
3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 4 syntheses or guidelines pooled it, 243 citations in OpenAlex.

  1. Methotrexate for juvenile idiopathic arthritis.The Cochrane database of systematic reviews · 2024
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  17. The emerging role of clinimetrics in pediatric rheumatology.Pediatric rheumatology online journal · 2026
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57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alessandro ConsolaroIstituto Giannina Gaslini, Genova, Italy. alessandroconsolaro@gaslini.org.
Gabriella GiancaneIstituto Giannina Gaslini, Genova, Italy.
Benedetta SchiappapietraIstituto Giannina Gaslini, Genova, Italy.
Sergio DavìIstituto Giannina Gaslini, Genova, Italy.
Serena CalandraIstituto Giannina Gaslini, Genova, Italy.
Stefano LanniIstituto Giannina Gaslini, Genova, Italy.
Angelo RavelliIstituto Giannina Gaslini, Genova, Italy.
Istituto Giannina Gaslini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Juvenile idiopathic arthritis (JIA), as a chronic condition, is associated with significant disease- and treatment-related morbidity, thus impacting children's quality of life. In order to optimize JIA management, the paediatric rheumatologist has begun to regularly use measurements of disease activity developed, validated and endorsed by international paediatric rheumatology professional societies in an effort to monitor the disease course over time and assess the efficacy of therapeutic interventions in JIA patients.A literature review was performed to describe the main outcome measures currently used in JIA patients to determine disease activity status.The Juvenile Disease Activity Score (JADAS), in its different versions (classic JADAS, JADAS-CRP and cJADAS) and the validated definitions of disease activity and response to treatment represent an important tool for the assessment of clinically relevant changes in disease activity, leading more and more to a treat-to-target strategy, based on a tight and thorough control of the patient condition. Moreover, in recent years, increasing attention on the incorporation of patient-reported or parent-reported outcomes (PRCOs), when measuring the health state of patients with paediatric rheumatic diseases has emerged.We think that the care of JIA patients cannot be possible without taking into account clinical outcome measures and, in this regard, further work is required.

Indexed as

Disease ManagementAdolescentArthritis, JuvenileChildDisease ProgressionHumansOutcome Assessment, Health CareQuality of LifeJuvenile idiopathic arthritisOutcome

Identifiers

PMID27089922
PMCPMC4836071
OpenAlexW2340414165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.