ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2016
Exposure to Violence and Virologic and Immunological Outcomes Among Youth With Perinatal HIV in the Pediatric HIV/AIDS Cohort Study.
Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01418014 (Adolescent Master Protocol), which is not on this map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Adolescent Master Protocol
Who cites it
20 citing papers in PubMed.
- The ethics of research involving biobanking specimens from Kenyan children and adolescents living with HIV: discrepancies between individual perceptions and policy considerations.BMC medical ethics · 2026Article
- Violence as an obstacle to HIV medication adherence and viral suppression: A daily diary investigation among adolescent boys.Social science & medicine (1982) · 2025Article
- A qualitative assessment of retention in HIV care among adolescents and young adults (AYA) living with HIV in New York City.AIDS care · 2024Article
- "We did more than survive": lessons learned from studies of risk and resilience of young people growing up with HIV and mental health needs.AIDS care · 2024Article
- Individual-, Interpersonal- and Institutional-Level Factors Associated with HIV Stigma Among Youth in Kenya.AIDS and behavior · 2023Article
- HIV and suicide risk across adolescence and young adulthood: an examination of socio-demographic, contextual and psychosocial risk factors for attempted suicide in a longitudinal cohort of ageing adolescents affected by HIV living in the New York City Area.Journal of the International AIDS Society · 2022Article
- Article
- Are we there yet? 40 years of successes and challenges for children and adolescents living with HIV.Journal of the International AIDS Society · 2021Article
- Past-Year Violence Victimization is Associated with Viral Load Failure Among HIV-Positive Adolescents and Young Adults.AIDS and behavior · 2021Article
- "We need our own clinics": Adolescents' living with HIV recommendations for a responsive health system.PloS one · 2021Article
- Examining the relationship between physical and sexual violence and psychosocial health in young people living with HIV in rural South Africa.Journal of the International AIDS Society · 2020Article
- Psychiatric trajectories across adolescence in perinatally HIV-exposed youth: the role of HIV infection and associations with viral load.AIDS (London, England) · 2020Article
- State-of-the-Science Review of Non-Chemical Stressors Found in a Child's Social Environment.International journal of environmental research and public health · 2019Review
- Nonadherence and unsuppressed viral load across adolescence among US youth with perinatally acquired HIV.AIDS (London, England) · 2019Article
- Gender-based violence and engagement in biomedical HIV prevention, care and treatment: a scoping review.BMC public health · 2019Article
- Mental Health Diagnoses, Symptoms, and Service Utilization in US Youth with Perinatal HIV Infection or HIV Exposure.AIDS patient care and STDs · 2019Article
- Multitype violence exposures and adolescent antiretroviral nonadherence in South Africa.AIDS (London, England) · 2018Article
- Childhood adversity increases the risk of onward transmission from perinatal HIV-infected adolescents and youth in South Africa.Child abuse & neglect · 2018Article
- High self-reported non-adherence to antiretroviral therapy amongst adolescents living with HIV in Malawi: barriers and associated factors.Journal of the International AIDS Society · 2017Article
- HIV is always with me: men living with perinatally acquired HIV and planning their families.Open access journal of contraception · 2017Article
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9 authors.
Funding
Abstract
purposeExposure to violence in childhood has been linked to adverse health outcomes. Little is known about the prevalence and relationship of youth and caregiver violence exposure to clinical outcomes among youth with perinatal human immunodeficiency virus (HIV) infection (PHIV). We evaluated associations of youth and caregiver violence exposure with unsuppressed viral load (VL) (HIV RNA > 400 copies/mL) and CD4% <25% among 8- to 15-year-old participants with PHIV in the Pediatric HIV/AIDS Cohort Study Adolescent Master Protocol.
methodsAnnual clinical examination, record abstraction, and interview data were collected, including youth report of recent exposure to violence and caregivers' self-report of being assaulted/abused in adulthood. Multivariable logistic regression methods were used to calculate adjusted odds ratios for unsuppressed VL and CD4% <25%, controlling for sociodemographic characteristics.
resultsAmong 268 youth with PHIV (53% girls, mean age 12.8 years, 21% white, 42% with household income <$20,000/year), 34% reported past year violence exposure; 30% had a caregiver who reported being assaulted in adulthood. One quarter of youth (24%) had unsuppressed VL and 22% had CD4% <25%. Youth who were exposed to violence in the past year versus those who were not had elevated odds of unsuppressed VL. Youth with indirect exposure to violence in the past year versus those without had elevated odds of unsuppressed VL and CD4% <25% in adjusted models.
conclusionsYouth with PHIV report a high prevalence of recent violence exposure, which was associated with poor virologic and immunologic outcomes. Reducing violence and providing support to youth with violence exposure and PHIV may improve health outcomes.
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