ArticleLangmuir : the ACS journal of surfaces and colloids2016
Modification of β-Sheet Forming Peptide Hydrophobic Face: Effect on Self-Assembly and Gelation.
Article in Langmuir : the ACS journal of surfaces and colloids, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The trial behind it
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Who cites it
28 citing papers in PubMed.
- In Vitro Screening of Short Synthetic Antimicrobial Peptides Toward Food-Relevant Microorganisms: Antifungal Activity and Molecular Docking Analysis.Microorganisms · 2026Article
- Charge Directed Selective Co-Assembly of Ionic Complementary Peptide Binary Mixtures.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Self-Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration.Advanced healthcare materials · 2026Article
- Controlling Supramolecular Assembly through Peptide Chirality.ACS applied materials & interfaces · 2025Article
- Unraveling the Atomistic Mechanism of Electrostatic Lateral Association of Peptide β-Sheet Structures and Its Role in Nanofiber Growth and Hydrogelation.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- RGD-functionalised self-assembling peptide hydrogel induces a proliferative profile in human osteoblasts in vitro.Journal of peptide science : an official publication of the European Peptide Society · 2025Article
- Nanotechnology in Drug Delivery: Anatomy and Molecular Insight into the Self-Assembly of Peptide-Based Hydrogels.Molecules (Basel, Switzerland) · 2024Review
- Effects of proline substitution/inclusion on the nanostructure of a self-assembling β-sheet-forming peptide.RSC advances · 2024Article
- Interactions and pattern formation in a macroscopic magnetocapillary SALR system of mermaid cereal.Nature communications · 2024Article
- Effect of Peptide-Polymer Host-Guest Electrostatic Interactions on Self-Assembling Peptide Hydrogels Structural and Mechanical Properties and Polymer Diffusivity.Biomacromolecules · 2024Article
- Genetically Fusing Order-Promoting and Thermoresponsive Building Blocks to Design Hybrid Biomaterials.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024Review
- Visualization of Self-Assembly and Hydration of a β-Hairpin through Integrated Small and Wide-Angle Neutron Scattering.Biomacromolecules · 2023Article
- Data-mining unveils structure-property-activity correlation of viral infectivity enhancing self-assembling peptides.Nature communications · 2023Article
- Advancements in Biosensors Based on the Assembles of Small Organic Molecules and Peptides.Biosensors · 2023Review
- Polysaccharide-based biopolymer hydrogels for heavy metal detection and adsorption.Journal of advanced research · 2023Review
- Hydrogels from the Assembly of SAA/Elastin-Inspired Peptides Reveal Non-Canonical Nanotopologies.Molecules (Basel, Switzerland) · 2022Article
- Controlling Doxorubicin Release from a Peptide Hydrogel through Fine-Tuning of Drug-Peptide Fiber Interactions.Biomacromolecules · 2022Article
- Spectroscopic and in silico investigation of the interaction between GH1 β-glucosidase and ginsenoside RbFood science & nutrition · 2021Article
- Role of Sheet-Edge Interactions in β-sheet Self-Assembling Peptide Hydrogels.Biomacromolecules · 2020Article
- Self-Assembling Peptides as an Emerging Platform for the Treatment of Metabolic Syndrome.International journal of nanomedicine · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
β-Sheet forming peptides have attracted significant interest for the design of hydrogels for biomedical applications. One of the main challenges is the control and understanding of the correlations between peptide molecular structure, the morphology, and topology of the fiber and network formed as well as the macroscopic properties of the hydrogel obtained. In this work, we have investigated the effect that functionalizing these peptides through their hydrophobic face has on their self-assembly and gelation. Our results show that the modification of the hydrophobic face results in a partial loss of the extended β-sheet conformation of the peptide and a significant change in fiber morphology from straight to kinked. As a consequence, the ability of these fibers to associate along their length and form large bundles is reduced. These structural changes (fiber structure and network topology) significantly affect the mechanical properties of the hydrogels (shear modulus and elasticity).
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Registered trials
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