ArticleBrain sciences2016
Wisteria Floribunda Agglutinin-Labeled Perineuronal Nets in the Mouse Inferior Colliculus, Thalamic Reticular Nucleus and Auditory Cortex.
Article in Brain sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Effects of Blueberry Supplementation on Depression and Anxiety Symptoms in a Rural Louisiana Population.Nutrients · 2025Trial
- Age-related differences in GABAergic synapses across the central inferior colliculus in the Fischer Brown Norway rat.Neurobiology of aging · 2025Article
- Distribution of perineuronal nets in the adult rat neocortex.Somatosensory & motor research · 2025Article
- Cell-Type-Specific Expression of Leptin Receptors in the Mouse Forebrain.International journal of molecular sciences · 2024Article
- Age-related upregulation of dense core vesicles in the central inferior colliculus.Frontiers in cellular neuroscience · 2024Article
- Neuroanatomical Alterations in the CNTNAP2 Mouse Model of Autism Spectrum Disorder.Brain sciences · 2023Article
- Cross-species conservation in the regulation of parvalbumin by perineuronal nets.Frontiers in neural circuits · 2023Article
- Age-related upregulation of perineuronal nets on inferior collicular cells that project to the cochlear nucleus.Frontiers in aging neuroscience · 2023Article
- Perineuronal Nets in the Prefrontal Cortex of a Schizophrenia Mouse Model: Assessment of Neuroanatomical, Electrophysiological, and Behavioral Contributions.International journal of molecular sciences · 2021Article
- Cholinergic boutons are closely associated with excitatory cells and four subtypes of inhibitory cells in the inferior colliculus.Journal of chemical neuroanatomy · 2021Article
- Inferior collicular cells that project to the auditory thalamus are increasingly surrounded by perineuronal nets with age.Neurobiology of aging · 2021Article
- Noise exposure alters MMP9 and brevican expression in the rat primary auditory cortex.BMC neuroscience · 2020Article
- The Density of Perineuronal Nets Increases With Age in the Inferior Colliculus in the Fischer Brown Norway Rat.Frontiers in aging neuroscience · 2020Article
- Inhibitory Projections in the Mouse Auditory Tectothalamic System.Brain sciences · 2018Article
- Perineuronal Nets in Spinal Motoneurones: Chondroitin Sulphate Proteoglycan around Alpha Motoneurones.International journal of molecular sciences · 2018Article
- Age-Related Deterioration of Perineuronal Nets in the Primary Auditory Cortex of Mice.Frontiers in aging neuroscience · 2016Article
- Organization of the Zone of Transition between the Pretectum and the Thalamus, with Emphasis on the Pretectothalamic Lamina.Frontiers in neuroanatomy · 2016Article
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4 authors.
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Abstract
Perineuronal nets (PNNs) are specialized extracellular matrix molecules that are associated with the closing of the critical period, among other functions. In the adult brain, PNNs surround specific types of neurons, however the expression of PNNs in the auditory system of the mouse, particularly at the level of the midbrain and forebrain, has not been fully described. In addition, the association of PNNs with excitatory and inhibitory cell types in these structures remains unknown. Therefore, we sought to investigate the expression of PNNs in the inferior colliculus (IC), thalamic reticular nucleus (TRN) and primary auditory cortex (A1) of the mouse brain by labeling with wisteria floribunda agglutinin (WFA). To aid in the identification of inhibitory neurons in these structures, we employed the vesicular GABA transporter (VGAT)-Venus transgenic mouse strain, which robustly expresses an enhanced yellow-fluorescent protein (Venus) natively in nearly all gamma-amino butyric acid (GABA)-ergic inhibitory neurons, thus enabling a rapid and unambiguous assessment of inhibitory neurons throughout the nervous system. Our results demonstrate that PNNs are expressed throughout the auditory midbrain and forebrain, but vary in their local distribution. PNNs are most dense in the TRN and least dense in A1. Furthermore, PNNs are preferentially associated with inhibitory neurons in A1 and the TRN, but not in the IC of the mouse. These data suggest regionally specific roles for PNNs in auditory information processing.
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