ArticleInternational journal of molecular sciences2016
Genome Sequence of the Fish Pathogen Yersinia ruckeri SC09 Provides Insights into Niche Adaptation and Pathogenic Mechanism.
Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Yersinia ruckeri Infection and Enteric Redmouth Disease among Endangered Chinese Sturgeons, China, 2022.Emerging infectious diseases · 2024Article
- Transmembrane Transcription Regulators Are Widespread in Bacteria and Archaea.Microbiology spectrum · 2023Article
- Pan-genome survey of the fish pathogen Yersinia ruckeri links accessory- and amplified genes to virulence.PloS one · 2023Article
- Transcriptome, intestinal microbiome and histomorphology profiling of differences in the response of Chinese sea bass (Frontiers in microbiology · 2023Article
- RNA-Seq and 16S rRNA Analysis Revealed the Effect of Deltamethrin on Channel Catfish in the Early Stage of Acute Exposure.Frontiers in immunology · 2022Article
- Delivering the pain: an overview of the type III secretion system with special consideration for aquatic pathogens.Veterinary research · 2021Review
- Phenotypic and genomic characterization of aMicrobial genomics · 2021Article
- Dual RNA-Seq of Trunk Kidneys Extracted From Channel Catfish Infected WithFrontiers in immunology · 2021Article
- Autophagy and Intracellular Membrane Trafficking Subversion by PathogenicBiomolecules · 2020Review
- Effects of Yersinia ruckeri invasion on the proteome of the Chinook salmon cell line CHSE-214.Scientific reports · 2020Article
- Effects of siRNA silencing on the susceptibility of the fish cell line CHSE-214 to Yersinia ruckeri.Veterinary research · 2020Article
- Review
- AInternational journal of molecular sciences · 2019Article
- Intracellular Bacterial Infections: A Challenge for Developing Cellular Mediated Immunity Vaccines for Farmed Fish.Microorganisms · 2018Review
- Invasion and replication of Yersinia ruckeri in fish cell cultures.BMC veterinary research · 2018Article
- The Infection Process ofFrontiers in cellular and infection microbiology · 2018Review
- pYR4 From a Norwegian Isolate ofFrontiers in cellular and infection microbiology · 2018Article
- The Promise of Whole Genome Pathogen Sequencing for the Molecular Epidemiology of Emerging Aquaculture Pathogens.Frontiers in microbiology · 2017Review
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Yersinia ruckeri is the etiologic agent of enteric red mouth disease (ERM), a severe fish disease prevailing in worldwide aquaculture industries. Here we report for the first time the complete genome of Y. ruckeri (Yersinia ruckeri) SC09, a highly virulent strain isolated from Ictalurus punctatus with severe septicemia. SC09 possesses a single chromosome of 3,923,491 base pairs, which contains 3651 predicted protein coding sequences (CDS), 19 rRNA genes, and 79 tRNA genes. Among the CDS, we have identified a Ysa locus containing genes encoding all the components of a type III secretion system (T3SS). Comparative analysis suggest that SC09-Ysa share extensive similarity in sequence, gene content, and gene arrangement with Salmonella enterica pathogenicity island 1 (SPI1) and chromosome-encoded T3SS from Yersinia enterocolitica biotype 1B. Furthermore, phylogenetic analysis shown that SC09-Ysa and SPI1-T3SS belong on the same branch of the phylogenetic tree. These results suggest that SC09-Ysa and SPI1-T3SS appear to mediate biological function to adapt to specific hosts with a similar niche, and both of them are likely to facilitate the development of an intracellular niche. In addition, our analysis also indicated that a substantial part of the SC09 genome might contribute to adaption in the intestinal microenvironment, including a number of proteins associated with aerobic or anaerobic respiration, signal transduction, and various stress reactions. Genomic analysis of the bacterium offered insights into the pathogenic mechanism associated with intracellular infection and intestinal survivability, which constitutes an important first step in understanding the pathogenesis of Y. ruckeri.
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