Evidence map›Paper›PMID 27088722›Full record

ArticleNature biotechnology2016

Sequencing wild and cultivated cassava and related species reveals extensive interspecific hybridization and genetic diversity.

Jessen V Bredeson, Jessica B Lyons, Simon E Prochnik, G Albert Wu, Cindy M Ha, Eric Edsinger-Gonzales, Jane Grimwood, Jeremy Schmutz, Ismail Y Rabbi, Chiedozie Egesi and 11 more

Abstract read
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In one paragraph

Article in Nature biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 188 papers.

0numbers the graph read from it
0cells of the map it votes in
188citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

188 citing papers in PubMed.

  1. Article
  2. The chromosome-level genomes of twoHorticulture research · 2026
    Article
  3. Adaptive Responses of Tropical Crops: A Multi-Scale Omics Integrated Perspective.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
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128 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Jessen V BredesonDepartment of Molecular and Cell Biology, University of California, Berkeley, California, USA.
Jessica B LyonsDepartment of Molecular and Cell Biology, University of California, Berkeley, California, USA.ORCID 0000-0002-3886-2146
Simon E ProchnikUnited States Department of Energy Joint Genome Institute (DOE JGI), Walnut Creek, California, USA.
G Albert WuUnited States Department of Energy Joint Genome Institute (DOE JGI), Walnut Creek, California, USA.
Cindy M HaDepartment of Molecular and Cell Biology, University of California, Berkeley, California, USA.
Eric Edsinger-GonzalesDepartment of Molecular and Cell Biology, University of California, Berkeley, California, USA.
Jane GrimwoodUnited States Department of Energy Joint Genome Institute (DOE JGI), Walnut Creek, California, USA.
Jeremy SchmutzUnited States Department of Energy Joint Genome Institute (DOE JGI), Walnut Creek, California, USA.
Ismail Y RabbiInternational Institute of Tropical Agriculture (IITA), Ibadan, Nigeria.
Chiedozie EgesiNational Root Crops Research Institute (NRCRI), Umudike, Nigeria.
Poasa NauluvulaDepartment of Agriculture, Ministry of Primary Industries, Koronivia Research Station, Fiji.
Vincent LebotCentre de coopération Internationale en Recherche Agronomique pour le Développement (CIRAD), Port-Vila, Vanuatu.
Joseph NdunguruMikocheni Agricultural Research Institute (MARI), Dar es Salaam, Tanzania.
Geoffrey MkamiloNaliendele Agricultural Research Institute (NARI), Mtwara, Tanzania.
Rebecca S BartDonald Danforth Plant Science Center, St. Louis, Missouri, USA.
Tim L SetterSection of Soil and Crop Sciences, School of Integrative Plant Science, Cornell University, Ithaca, New York, USA.
Roslyn M GleadowSchool of Biological Sciences, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0003-4756-0411
Peter KulakowInternational Institute of Tropical Agriculture (IITA), Ibadan, Nigeria.
Morag E FergusonInternational Institute of Tropical Agriculture (IITA), Nairobi, Kenya.
Steve RounsleyDow AgroSciences, Indianapolis, Indiana, USA.ORCID 0000-0002-3016-6795
Daniel S RokhsarDepartment of Molecular and Cell Biology, University of California, Berkeley, California, USA.

Funding

Genome Sequencer FLXS10RR029668 · NCRR · UNIVERSITY OF CALIFORNIA BERKELEY · PI NGAI, JOHN J. · 2010 to 2010
$623k
Illumina Sequencer to Facilitate Functional Genomics at BerkeleyS10RR027303 · NCRR · UNIVERSITY OF CALIFORNIA BERKELEY · PI TAYLOR, JOHN W. · 2010 to 2010
$500k
NCRR NIH HHS S10 RR027303NCRR NIH HHS S10 RR029668
6 · The paper itself

Abstract

Cassava (Manihot esculenta) provides calories and nutrition for more than half a billion people. It was domesticated by native Amazonian peoples through cultivation of the wild progenitor M. esculenta ssp. flabellifolia and is now grown in tropical regions worldwide. Here we provide a high-quality genome assembly for cassava with improved contiguity, linkage, and completeness; almost 97% of genes are anchored to chromosomes. We find that paleotetraploidy in cassava is shared with the related rubber tree Hevea, providing a resource for comparative studies. We also sequence a global collection of 58 Manihot accessions, including cultivated and wild cassava accessions and related species such as Ceará or India rubber (M. glaziovii), and genotype 268 African cassava varieties. We find widespread interspecific admixture, and detect the genetic signature of past cassava breeding programs. As a clonally propagated crop, cassava is especially vulnerable to pathogens and abiotic stresses. This genomic resource will inform future genome-enabled breeding efforts to improve this staple crop.

Indexed as

Chromosome MappingConserved SequenceDNA, PlantGenetic VariationGenome, PlantHybridization, GeneticManihotPlant BreedingSequence Analysis, DNASpecies SpecificityDNA, Plant

Identifiers

PMID27088722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.