Evidence map›Paper›PMID 27088660›Full record

ReviewVirulence2016

Approved and novel strategies in diagnostics of rat bite fever and other Streptobacillus infections in humans and animals.

Tobias Eisenberg, Christa Ewers, Jörg Rau, Valerij Akimkin, Werner Nicklas

Open access · goldAbstract readReview
In one paragraph

Review in Virulence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Rat-Bite Fever due to the genusAIMS microbiology · 2024
    Review
  9. Septic arthritis complicatingFrontiers in medicine · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. The Brief Case: Rat Bite Fever from a Kiss.Journal of clinical microbiology · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Tobias Eisenberga Hessisches Landeslabor , Gießen , Germany.
Christa Ewersb Institut für Hygiene und Infektionskrankheiten der Tiere, Justus-Liebig-Universität Gießen , Gießen , Germany.
Jörg Rauc Chemisches und Veterinäruntersuchungsamt Stuttgart , Fellbach , Germany.
Valerij Akimkinc Chemisches und Veterinäruntersuchungsamt Stuttgart , Fellbach , Germany.
Werner Nicklasd Deutsches Krebsforschungszentrum , Heidelberg , Germany.
Chemisches und Veterinäruntersuchungsamt Stuttgart · DEDKFZ-ZMBH Alliance · DEUniversity of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rat bite fever (RBF), a worldwide occurring and most likely under-diagnosed zoonosis caused by Streptobacillus moniliformis, represents the most prominent disease of Streptobacillus infections. Recently, novel members have been described, from which a reservoir in rats and other animal species and a zoonotic potential can be assumed. Despite regularly published case reports, diagnostics of RBF continues to represent a 'diagnostic dilemma', because the mostly applied 16S rRNA sequence analysis may be uncertain for proper pathogen identification. Virtually nothing is known regarding prevalence in humans and animal reservoirs. For a realistic assessment of the pathogen's spread, epidemiology and virulence traits, future studies should focus on the genomic background of Streptobacillus. Full genome sequence analyses of a representative collection of strains might facilitate to unequivocally identify and type isolates. Prevalence studies using selective enrichment mechanisms may also enable the isolation of novel strains and candidate species of this neglected group of microorganisms.

Indexed as

AnimalsAnti-Bacterial AgentsFusobacterium InfectionsGenes, EssentialHigh-Throughput Nucleotide SequencingHumansMicrobial Sensitivity TestsMicroscopy, ElectronMolecular Diagnostic TechniquesRat-Bite FeverRatsRNA, Ribosomal, 16SSerologySpectrophotometry, InfraredStreptobacillusZoonosesAnti-Bacterial AgentsRNA, Ribosomal, 16S16S rRNA gene sequencingantimicrobial sensitivity testingelectron microscopyFourier transform infrared spectroscopyhousekeeping genesMALDI-TOF MSnext generation sequencingrat bite feverserology

Identifiers

PMID27088660
PMCPMC4991327
OpenAlexW2341588687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.