ArticlePloS one2016
Endoscopic Tumor Length Should Be Reincluded in the Esophageal Cancer Staging System: Analyses of 662 Consecutive Patients.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prognostic impact of tumor length in esophageal Cancer: a systematic review and Meta-analysis.BMC cancer · 2021Pooled it
- Pooled it
- Development and validation of a nomogram for prediction of cervical lymph node metastasis in middle and lower thoracic esophageal squamous cell carcinoma.BMC gastroenterology · 2022Article
- Optimal Treatment of cT2N0 Esophageal Carcinoma: Is Upfront Surgery Really the Way?Annals of surgical oncology · 2021Article
- The role of endoscopic tumor length in resected esophageal squamous cell carcinoma: a retrospective study.Journal of thoracic disease · 2021Article
- Esophageal Cancer: An Updated Surveillance Epidemiology and End Results Database Analysis.World journal of oncology · 2020Article
- Tumor Size as a Critical Prognostic Factor in T1-2 Stage Esophageal Cancer.Gastroenterology research and practice · 2020Article
- Prognostic value of tumor length and diameter for esophageal squamous cell cancer patients treated with definitive (chemo)radiotherapy: Potential indicators for nonsurgical T staging.Cancer medicine · 2019Article
- Expression of serum AMPD1 in thyroid carcinoma and its clinical significance.Experimental and therapeutic medicine · 2018Article
- miR302a inhibits the proliferation of esophageal cancer cells through the MAPK and PI3K/Akt signaling pathways.Oncology letters · 2018Article
- Survival based radiographic-grouping for esophageal squamous cell carcinoma may impact clinical T stage.Oncotarget · 2018Article
- Novel BRCA2-Interacting Protein, LIMD1, Is Essential for the Centrosome Localization of BRCA2 in Esophageal Cancer Cell.Oncology research · 2016Article
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9 authors.
Funding
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Abstract
Esophageal cancer represents the 6th cause of cancer mortality in the World. New treatments led to outcome improvements, but patient selection and prognostic stratification is a critical aspect to gain maximum benefit from therapies. Today, patients are stratified into 9 prognostic groups, according to a staging system developed by the American Joint Committee on Cancer. Recently, trying to better select patients with curing possibilities several authors are reconsidering tumor length as a valuable prognostic parameter. Specifically, endoscopic tumor length can be easily measured with an esophageal endoscopy and, if its utility in esophageal cancer staging is demonstrated, it may represent a simple method to identify high risk patients and an easy-to-obtain variable in prognostic stratification. In this study we retrospectively analyzed 662 patients treated for esophageal cancer, stratified according to cancer histology and current staging system, to assess the possible role of endoscopic tumor length. We found a significant correlation between endoscopic tumor length, current staging parameters and 5-year survival, proving that endoscopic tumor length may be used as a simple risk stratification tool. Our results suggest a possible indication for preoperative therapy in early stage squamocellular carcinoma patients without lymph nodes involvement, who are currently treated with surgery alone.
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