ArticleNature materials2016
Bioresorbable silicon electronics for transient spatiotemporal mapping of electrical activity from the cerebral cortex.
Article in Nature materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
141 citing papers in PubMed, 1 synthesis or guideline pooled it, 497 citations in OpenAlex.
- Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics.Frontiers in bioengineering and biotechnology · 2021Pooled it
- Bioresorbable and optically readable triboelectric implants enabled by nanoscale iridophosphors.Nature nanotechnology · 2026Article
- In Vivo Continuous Biosensing: Design Considerations and Emerging Technologies.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Active devices and systems for closed-loop neuromodulation.Microsystems & nanoengineering · 2026Review
- Flexible biodegradable wireless battery-free integrated theranostic adhesive patch.Bioactive materials · 2026Article
- Design, Implantation, and Biodistribution Study of a Resorbable Epidural Electrode Array Embedding Bioresorbable Polymeric Conductive Ink.ACS applied materials & interfaces · 2026Article
- Vertically Aligned Nanopillar Electrodes: Engineered Interfaces for Electrophysiology and Cell-Electrode Coupling.Small methods · 2026Review
- Thermally Degradable Biocompatible Hydrogel as Transient Encapsulation Coating for Implantable Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Brain-Adhesive Bioelectronics With Shape-Morphable and Biodegradable Properties for Stable Brain Signal Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Two-dimensional semiconductor-based active array for high-fidelity spatiotemporal monitoring of neural activities.Nature materials · 2026Article
- A programmable bioresorbable electrochemical microneedle sensor array for perioperative monitoring of organ health.Nature biomedical engineering · 2026Article
- First-principles approaches and concepts to simulate electrochemical interfaces.Nature reviews. Chemistry · 2026Review
- Biodegradable Implantable Electronics with Wireless Technology for Real-Time Clinical Applications.Advanced healthcare materials · 2026Review
- An Active, Multimodal Neural Interface for Real-Time Monitoring of Cortical Electrical, Thermal, and Optical Dynamics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Recent Advances in Stimuli-Responsive Materials and Soft Robotic Actuators for Bioelectronic Medicine.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Substrate-Dependent Performance of ZnTTBPc-PMMA Composite Films on Rigid, Flexible, and Sustainable Materials for Wearable Devices.Polymers · 2025Article
- Materials and device strategies to enhance spatiotemporal resolution in bioelectronics.Nature reviews. Materials · 2025Article
- Advances in Symbiotic Bioabsorbable Devices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Electrical Stimulation Therapy - Dedicated to the Perfect Plastic Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
81 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 6 institutions in 2 countries.
Funding
Abstract
Bioresorbable silicon electronics technology offers unprecedented opportunities to deploy advanced implantable monitoring systems that eliminate risks, cost and discomfort associated with surgical extraction. Applications include postoperative monitoring and transient physiologic recording after percutaneous or minimally invasive placement of vascular, cardiac, orthopaedic, neural or other devices. We present an embodiment of these materials in both passive and actively addressed arrays of bioresorbable silicon electrodes with multiplexing capabilities, which record in vivo electrophysiological signals from the cortical surface and the subgaleal space. The devices detect normal physiologic and epileptiform activity, both in acute and chronic recordings. Comparative studies show sensor performance comparable to standard clinical systems and reduced tissue reactivity relative to conventional clinical electrocorticography (ECoG) electrodes. This technology offers general applicability in neural interfaces, with additional potential utility in treatment of disorders where transient monitoring and modulation of physiologic function, implant integrity and tissue recovery or regeneration are required.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.