Evidence map›Paper›PMID 27088098›Full record

ReviewJournal of immunology research2016

Dendritic Cells and Their Role in Cardiovascular Diseases: A View on Human Studies.

Maja-Theresa Dieterlen, Katja John, Hermann Reichenspurner, Friedrich W Mohr, Markus J Barten

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Observational
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maja-Theresa DieterlenDepartment of Cardiac Surgery, Heart Center, Helios Clinic, University Hospital Leipzig, 04289 Leipzig, Germany.ORCID 0000-0002-5503-9901
Katja JohnDepartment of Cardiac Surgery, Heart Center, Helios Clinic, University Hospital Leipzig, 04289 Leipzig, Germany.
Hermann ReichenspurnerDepartment of Cardiovascular Surgery, University Heart Center Hamburg, 20246 Hamburg, Germany.
Friedrich W MohrDepartment of Cardiac Surgery, Heart Center, Helios Clinic, University Hospital Leipzig, 04289 Leipzig, Germany.
Markus J BartenDepartment of Cardiovascular Surgery, University Heart Center Hamburg, 20246 Hamburg, Germany.ORCID 0000-0002-0785-0783
University Hospital Leipzig · DEUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antigen-presenting dendritic cells (DCs) are key to the immunological response, with different functions ascribed ranging from cellular immune activation to induction of tolerance. Such immunological responses are involved in the pathophysiological mechanisms of cardiovascular diseases, with DCs shown to play a role in atherosclerosis, hypertension, and heart failure and most notably following heart transplantation. A better understanding of the interplay between the immune system and cardiovascular diseases will therefore be critical for developing novel therapeutic treatments as well as innovative monitoring tools for disease progression. As such, the present review will provide an overview of DCs involvement in the pathophysiology of cardiovascular diseases and how targeting these cells may have beneficial effects for the prognosis of patients.

Indexed as

Antigen PresentationAntigensAtherosclerosisClinical Trials as TopicCoronary Artery BypassDendritic CellsHeart FailureHeart TransplantationHumansHypertensionImmune ToleranceImmunity, InnateAntigens

Identifiers

PMID27088098
PMCPMC4818818
OpenAlexW2300364145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.