Evidence map›Paper›PMID 27088051›Full record

ArticleInternational journal of clinical medicine

Impact of Maintenance Steroids versus Rapid Steroid Withdrawal in African-American Kidney Transplant Recipients: Comparison of Two Urban Centers.

W James Chon, Amishi Desai, Coady Wing, Divya Arwindekar, Ignatius Y S Tang, Michelle A Josephson, Sanjeev Akkina

Abstract read
In one paragraph

Article in International journal of clinical medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

W James ChonDepartment of Medicine, Division of Nephrology, University of Chicago Medicine, Chicago, IL, USA.
Amishi DesaiDepartment of Medicine, Division of Nephrology, Loyola University Medical Center, Maywood, IL, USA.
Coady WingSchool of Public and Environmental Affairs, Indiana University, Bloomington, IN, USA.
Divya ArwindekarDepartment of Medicine, Division of Nephrology, University of Illinois Hospital & Health Sciences System, Chicago, IL, USA.
Ignatius Y S TangDepartment of Medicine, Division of Nephrology, University of Illinois Hospital & Health Sciences System, Chicago, IL, USA; Department of Medicine, Division of Nephrology, Jesse Brown VA Medical Center, Chicago, IL, USA.
Michelle A JosephsonDepartment of Medicine, Division of Nephrology, University of Chicago Medicine, Chicago, IL, USA.
Sanjeev AkkinaDepartment of Medicine, Division of Nephrology, Loyola University Medical Center, Maywood, IL, USA.

Funding

Novel Biomarkers in Interstitial Fibrosis/Tubular Atrophy in Kidney TransplantsK23DK084121 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AKKINA, SANJEEV KUMAR · 2009 to 2013
$760k
NIDDK NIH HHS K23 DK084121
6 · The paper itself

Abstract

backgroundRapid steroid withdrawal (RSW) is used increasingly in kidney transplantation but long-term outcomes in African-American (AA) recipients are not well known. We compared 1 and 5 year transplant outcomes in a large cohort of AA patients who were maintained on continued steroid therapy (CST) to those who underwent RSW.

methodsPost-transplant courses of A as receiving kidney allografts from 2003-2011 at two urban transplant centers in Chicago were followed. Prior to outcome analysis, we used Inverse Probability of Treatment Weights (IPTW) to match the two groups on a set of baseline risk factors. Graft and patient survival, GFR at 1 and 5 years, incidence and type of rejection, incidence of post-transplant diabetes mellitus (PTDM), delayed graft function, CMV and BK viremia were compared.

resultsThere were 150 AA recipients in the CST analytic group and 157 in the RSW analytic group. Graft and patient survival was similar between the two groups. Rates of CMV viremia were higher in the RSW compared to the CST analytic group at 1 year. Biopsy-proven acute rejection and PTDM were similar between the RSW and CST groups.

conclusionsIn AA recipients, RSW has similar long-term outcomes to CST.

Indexed as

African-AmericansKidney TransplantSteroid Maintenance

Identifiers

PMID27088051
PMCPMC4829964

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.