Evidence map›Paper›PMID 27087995›Full record

ArticleBJPsych bulletin2016

First-generation antipsychotics: not gone but forgotten.

Claire R M Dibben, Golam M Khandaker, Benjamin R Underwood, Christopher O'Loughlin, Catherine Keep, Louisa Mann, Peter B Jones

Abstract read
In one paragraph

Article in BJPsych bulletin, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Gaps in Psychiatric Training Could Challenge Delivery of Optimal Schizophrenia Pharmacotherapy.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2018
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Claire R M DibbenNorfolk and Suffolk NHS Foundation Trust, UK.
Golam M KhandakerUniversity of Cambridge, UK; Cambridgeshire and Peterborough NHS Foundation Trust, UK.
Benjamin R UnderwoodCambridgeshire and Peterborough NHS Foundation Trust, UK.
Christopher O'LoughlinCambridgeshire and Peterborough NHS Foundation Trust, UK.
Catherine KeepNorfolk and Suffolk NHS Foundation Trust, UK.
Louisa MannCambridgeshire and Peterborough NHS Foundation Trust, UK.
Peter B JonesUniversity of Cambridge, UK; Cambridgeshire and Peterborough NHS Foundation Trust, UK.

Funding

Wellcome Trust 093875
6 · The paper itself

Abstract

Aims and method To identify training needs of the next generation of psychiatrists and barriers in prescribing first-generation antipsychotics (FGAs). We have surveyed psychiatry trainees in East Anglia with regard to their training experience, knowledge and attitudes to the use of oral FGAs as regular medication. Results Two-thirds of trainees were aware that first- and second-generation antipsychotics (SGAs) have similar efficacy, and a similar proportion perceived the older drugs to have more or 'stronger' side-effects. Lack of training experience was noted as the second leading concern for prescribing FGAs. A quarter of trainees received no training exposure to the older drugs and two-thirds had never initiated these drugs themselves. Although nearly 90% of trainees felt confident about initiating an oral SGA as a regular medication, only about 40% felt confident with FGAs (P<0.001). Clinical implications The survey highlights worrying gaps in training. FGAs can be used effectively, minimising side-effects, by careful dose titration, avoiding antipsychotic polypharmacy, high-dose, and high-potency drugs, thus ensuring they are not lost to future generations of psychiatrists.

Identifiers

PMID27087995
PMCPMC4817655

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.