Evidence map›Paper›PMID 27087882›Full record

ArticleInternational journal of statistics in medical research

The Validity of Disease-specific Quality of Life Attributions Among Adults with Multiple Chronic Conditions.

John E Ware, Barbara Gandek, Jeroan Allison

Open access · diamondAbstract read
In one paragraph

Article in International journal of statistics in medical research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Impact of comorbid conditions on disease-specific quality of life in older men and women with atrial fibrillation.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
  8. Improving CKD-Specific Patient-Reported Measures of Health-Related Quality of Life.Journal of the American Society of Nephrology : JASN · 2019
    Article
  9. A method to create a standardized generic and condition-specific patient-reported outcome measure for patient care and healthcare improvement.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
  10. Investigation Of Obesity-Related Mortality Rates In Delaware.American journal of health sciences · 2017
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

John E WareUniversity of Massachusetts Medical School, Worcester, MA; John Ware Research Group, Watertown, MA.
Barbara GandekUniversity of Massachusetts Medical School, Worcester, MA; John Ware Research Group, Watertown, MA.
Jeroan AllisonUniversity of Massachusetts Medical School, Worcester, MA.
University of Massachusetts Chan Medical School · US

Funding

Computerized Adaptive Assessment of Disease ImpactR44AG025589 · NIA · JOHN WARE RESEARCH GROUP, INC. · PI WARE, JOHN E · 2009 to 2011
$3.0M
Measuring Multimorbidity with Individualized Disease-specific QOL Impact ScalesR21HS023117 · AHRQ · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI WARE, JOHN E · 2014 to 2014
$180k
AHRQ HHS R21 HS023117NIA NIH HHS R44 AG025589
6 · The paper itself

Abstract

backgroundA crucial assumption underlying all disease-specific quality of life (QOL) measures, that patients can validly differentiate a specific disease

methodsAdults age 18 and older (N=4,480) sampled from eight pre-identified condition groups (asthma, COPD, angina/MI with angina, congestive heart failure, diabetes, chronic kidney disease, osteoarthritis, rheumatoid arthritis) completed an Internet survey. Comorbid conditions were determined using a 35-condition checklist. Product-moment correlations were analyzed separately by pre-identified condition group using the multitrait-multimethod of construct validation, where traits were defined by 9-26 conditions and each condition was measured by two methods: disease severity rating and Disease-specific Quality of Life Impact Scale (QDIS) global rating. A third method (symptom or clinical marker) was available for the eight pre-identified conditions.

resultsIn support of convergent validity, 22 of 24 convergent correlations were substantial (r=0.38-0.84, median=0.53). In support of discriminant validity, 833 of 924 tests (90.2%) yielded significantly higher convergent than discriminant correlations across the eight pre-identified conditions. Exceptions to this pattern of results were most often observed for comorbid conditions within the same clinical area.

conclusionsCollectively, convergent and discriminant test results support the construct validity of disease-specific QOL impact attributions across MCC within the eight pre-identified conditions. Noteworthy exceptions should be considered when interpreting some specific QOL impact attributions and warrant further study. Pursuit of a summary disease-specific QOL impact score standardized across MCC is recommended.

Indexed as

Disease-specific measuresHealth-related quality of lifeMultiple chronic conditionsMultitrait-multimethod analysisPatient-reported outcomesValidity

Identifiers

PMID27087882
PMCPMC4831653
OpenAlexW2265167193

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.