ArticleJournal of epidemiology2016
Splenectomy Correlates With Increased Risk of Acute Pancreatitis: A Case-Control Study in Taiwan.
Article in Journal of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Organ Crosstalk: The Role of Spleen.Phenomics (Cham, Switzerland) · 2025Review
- Nicotinic stimulation of splenic T cells is protective in endoscopic retrograde cholangiopancreatography-induced acute pancreatitis in mice.American journal of physiology. Gastrointestinal and liver physiology · 2022Article
- Abnormalities of the composition of the gut microbiota and short-chain fatty acids in mice after splenectomy.Brain, behavior, & immunity - health · 2021Article
- The role of splenectomy in lipid metabolism and atherosclerosis (AS).Lipids in health and disease · 2018Review
- Population-based cohort study examining the association between splenectomy and empyema in adults in Taiwan.BMJ open · 2017Article
- Risk of pneumonia among patients with splenectomy: a retrospective population-based cohort study.Annals of Saudi medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of the study was to investigate the association between splenectomy and acute pancreatitis.
methodsWe conducted a case-control study using the database of the Taiwan National Health Insurance Program. We included 7666 subjects aged 20-84 years with first-time acute pancreatitis during the period of 1998-2011 as cases and 30 664 randomly selected subjects without acute pancreatitis as controls. Both cases and controls were matched for sex, age, and index year of acute pancreatitis diagnosis. The association of acute pancreatitis with splenectomy was examined using a multivariable unconditional logistic regression model and reported as an odds ratio and its 95% confidence interval (CI).
resultsAfter adjustment for covariables, the adjusted odds ratio of acute pancreatitis was 2.90 for subjects with splenectomy (95% CI, 1.39-6.05) compared with subjects without splenectomy.
conclusionsSplenectomy is associated with acute pancreatitis. Further studies are necessary to clarify the underlying mechanism.
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Registered trials
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