Evidence map›Paper›PMID 27086316›Full record

ReviewCurrent psychiatry reports2016

Combining Pharmacological and Psychological Treatments for Binge Eating Disorder: Current Status, Limitations, and Future Directions.

Carlos M Grilo, Deborah L Reas, James E Mitchell

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Current psychiatry reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
8.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
  5. Trial
  6. Trial
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  9. Review
  10. Current Discoveries and Future Implications of Eating Disorders.International journal of environmental research and public health · 2023
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Binge eating disorder hidden behind a wall of anxiety disorders.Journal of psychiatry & neuroscience : JPN · 2021
    Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Carlos M GriloDepartment of Psychiatry, School of Medicine, Yale University, New Haven, CT, USA. carlos.grilo@yale.edu.
Deborah L ReasRegional Department for Eating Disorders, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
James E MitchellNeuropsychiatric Research Institute, Fargo, ND, USA.
Neuropsychiatric Research Institute · USOslo University Hospital · NOYale University · US

Funding

Mid-Career Investigator Award in Eating and WeightK24DK070052 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M · 2005 to 2015
$1.4M
NIDDK NIH HHS K24 DK070052
6 · The paper itself

Abstract

Binge eating disorder (BED) is characterized by recurrent binge eating and marked distress about binge eating without the extreme compensatory behaviors for weight control that characterize other eating disorders. BED is prevalent, associated strongly with obesity, and is associated with heightened levels of psychological, psychiatric, and medical concerns. This article provides an overview of randomized controlled treatments for combined psychological and pharmacological treatment of BED to inform current clinical practice and future treatment research. In contrast to the prevalence and significance of BED, to date, limited research has been performed on combining psychological and pharmacological treatments for BED to enhance outcomes. Our review here found that combining certain medications with cognitive behavioral therapy (CBT) or behavioral weight loss (BWL) interventions produces superior outcomes to pharmacotherapy only but does not substantially improve outcomes achieved with CBT/BWL only. One medication (orlistat) has improved weight losses with CBT/BWL albeit minimally, and only one medication (topiramate) has enhanced reductions achieved with CBT in both binge eating and weight. Implications for future research are discussed.

Indexed as

Cognitive Behavioral TherapyAnti-Obesity AgentsBinge-Eating DisorderBulimia NervosaFructoseHumansLactonesObesityOrlistatRandomized Controlled Trials as TopicTopiramateWeight LossAnti-Obesity AgentsFructoseLactonesOrlistatTopiramateBehavioral weight lossBinge eating disorderCognitive behavioral therapyMedicationObesityPharmacotherapy

Identifiers

PMID27086316
OpenAlexW2336056370

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.