Evidence map›Paper›PMID 27086033›Full record

ArticleJournal of medical systems2016

Regional Image Features Model for Automatic Classification between Normal and Glaucoma in Fundus and Scanning Laser Ophthalmoscopy (SLO) Images.

Muhammad Salman Haleem, Liangxiu Han, Jano van Hemert, Alan Fleming, Louis R Pasquale, Paolo S Silva, Brian J Song, Lloyd Paul Aiello

Open access · hybridAbstract read
In one paragraph

Article in Journal of medical systems, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Artificial intelligence in the anterior segment of eye diseases.International journal of ophthalmology · 2024
    Review
  3. Article
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  5. Article
  6. Article
  7. Practice Guidelines for Ocular Telehealth-Diabetic Retinopathy, Third Edition.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2020
    Article
  8. Telemedicine for Glaucoma: Guidelines and Recommendations.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2020
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Macular Optical Coherence Tomography Imaging in Glaucoma.Journal of ophthalmic & vision research
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Muhammad Salman HaleemManchester Metropolitan University, School of Computing, Mathematics and Digital Technology, Manchester, M1 5GD, UK. m.haleem@mmu.ac.uk.
Liangxiu HanManchester Metropolitan University, School of Computing, Mathematics and Digital Technology, Manchester, M1 5GD, UK.
Jano van HemertOptos, plc, Queensferry House, Carnegie Business Campus, Enterprise Way, Dunfermline, KY11 8GR, Scotland, UK.
Alan FlemingOptos, plc, Queensferry House, Carnegie Business Campus, Enterprise Way, Dunfermline, KY11 8GR, Scotland, UK.
Louis R PasqualeMassachusetts Eye and Ear Infirmary, Harvard Medical School, Department of Ophthalmology, Boston, MA, USA.
Paolo S SilvaBeetham Eye Institute, Joslin Diabetes Center, Harvard Medical School, Department of Ophthalmology, Boston, MA, USA.
Brian J SongMassachusetts Eye and Ear Infirmary, Harvard Medical School, Department of Ophthalmology, Boston, MA, USA.
Lloyd Paul AielloBeetham Eye Institute, Joslin Diabetes Center, Harvard Medical School, Department of Ophthalmology, Boston, MA, USA.
Digital Catapult · GBJoslin Diabetes Center · USManchester Metropolitan University · GBHarvard University · USMassachusetts Eye and Ear Infirmary · US

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI LAURIE J GOODYEAR · 1986 to 2026
$50.5M
Mass Eye and Ear-Vision Clinical Scientist Development ProgramK12EY016335 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Reza Dana · 2004 to 2026
$12.3M
NEI NIH HHS 5K12EY016335NEI NIH HHS K12 EY016335NIDDK NIH HHS P30 DK036836
6 · The paper itself

Abstract

Glaucoma is one of the leading causes of blindness worldwide. There is no cure for glaucoma but detection at its earliest stage and subsequent treatment can aid patients to prevent blindness. Currently, optic disc and retinal imaging facilitates glaucoma detection but this method requires manual post-imaging modifications that are time-consuming and subjective to image assessment by human observers. Therefore, it is necessary to automate this process. In this work, we have first proposed a novel computer aided approach for automatic glaucoma detection based on Regional Image Features Model (RIFM) which can automatically perform classification between normal and glaucoma images on the basis of regional information. Different from all the existing methods, our approach can extract both geometric (e.g. morphometric properties) and non-geometric based properties (e.g. pixel appearance/intensity values, texture) from images and significantly increase the classification performance. Our proposed approach consists of three new major contributions including automatic localisation of optic disc, automatic segmentation of disc, and classification between normal and glaucoma based on geometric and non-geometric properties of different regions of an image. We have compared our method with existing approaches and tested it on both fundus and Scanning laser ophthalmoscopy (SLO) images. The experimental results show that our proposed approach outperforms the state-of-the-art approaches using either geometric or non-geometric properties. The overall glaucoma classification accuracy for fundus images is 94.4% and accuracy of detection of suspicion of glaucoma in SLO images is 93.9 %.

Indexed as

Diagnosis, Computer-AssistedAlgorithmsFundus OculiGlaucomaHumansImage Interpretation, Computer-AssistedMachine LearningOphthalmoscopyComputer-aided diagnosisFundus cameraGlaucomaImage processing and analysisMachine learningScanning laser ophthalmoscope

Identifiers

PMID27086033
PMCPMC4834108
OpenAlexW2338203391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.