Evidence map›Paper›PMID 27085869›Full record

ArticleSurgery today2016

Sublobar resection versus lobectomy for stage I non-small cell lung cancer: an appropriate choice in elderly patients?

Alfonso Fiorelli, Francesco Paolo Caronia, Niccolò Daddi, Domenico Loizzi, Luca Ampollini, Nicoletta Ardò, Luigi Ventura, Paolo Carbognani, Rossella Potenza, Francesco Ardissone and 5 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgery today, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Trial
  2. A novel nomogram incorporating LASSO and Cox regression analyses for predicting survival in early-stage non-small cell lung cancer patients following sublobectomy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  8. [Surgery of old people-Thoracic surgery].Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alfonso FiorelliThoracic Surgery Unit, Second University of Naples, Piazza Miraglia, 2, 80138, Naples, Italy. alfonso.fiorelli@unina2.it.
Francesco Paolo CaroniaThoracic Surgery Unit, Istituto Oncologico del Mediterraneo, Catania, Italy.
Niccolò DaddiThoracic Surgery Unit, University of Bologna, Bologna, Italy.
Domenico LoizziThoracic Surgery Unit, University of Foggia, Foggia, Italy.
Luca AmpolliniThoracic Surgery Unit, University of Parma, Parma, Italy.
Nicoletta ArdòThoracic Surgery Unit, University of Foggia, Foggia, Italy.
Luigi VenturaThoracic Surgery Unit, University of Parma, Parma, Italy.
Paolo CarbognaniThoracic Surgery Unit, University of Parma, Parma, Italy.
Rossella PotenzaThoracic Surgery Unit, University of Perugia, Perugia, Italy.
Francesco ArdissoneThoracic Surgery Unit, San Luigi Hospital, University of Turin, Turin, Italy.
Francesco SollittoThoracic Surgery Unit, University of Foggia, Foggia, Italy.
Sandro MattioliThoracic Surgery Unit, University of Bologna, Bologna, Italy.
Francesco PumaThoracic Surgery Unit, University of Perugia, Perugia, Italy.
Mario SantiniThoracic Surgery Unit, Second University of Naples, Piazza Miraglia, 2, 80138, Naples, Italy.
Mark RagusaThoracic Surgery Unit, University of Terni, Terni, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposesThe aim of this study was to evaluate whether sublobar resection could achieve recurrence and survival rates equivalent to lobectomy in high-risk elderly patients.

methodsWe conducted a retrospective multicenter study that including all consecutive patients (aged >75 years) who underwent operation for clinical stage I non-small cell lung cancer (NSCLC). The clinicopathological data, postoperative morbidity and mortality, recurrence rate and vital status were retrieved. The overall survival, cancer-specific survival and disease-free survival were also assessed.

resultsTwo hundred and thirty-nine patients (median age 78 years) were enrolled. Lobectomies were performed in 149 (62.3 %) patients and sublobar resections in 90 (39 segmentectomies, 51 wedge resections). There were no differences in the recurrence rates following lobar versus sublobar resections (19 versus 23 %, respectively; p = 0.5) or the overall survival (p = 0.1), cancer-specific survival (p = 0.3) or disease-free survival (p = 0.1). After adjusting for 1:1 propensity score matching and a matched pair analysis, the results remained unchanged. A tumor size >2 cm and pN2 disease were independent negative prognostic factors in unmatched (p = 0.01 and p = 0.0003, respectively) and matched (p = 0.02 and p = 0.005, respectively) analyses.

conclusionsHigh-risk elderly patients may benefit from sublobar resection, which provides an equivalent long-term survival compared to lobectomy.

Indexed as

AgedAged, 80 and overCarcinoma, Non-Small-Cell LungFemaleHumansLung NeoplasmsMaleNeoplasm StagingPneumonectomyRecurrenceRetrospective StudiesRiskSurvival RateTreatment OutcomeElderlyLobectomyNon-small cell lung cancerSublobar resectionSurgery

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.