ReviewSeminars in nephrology2016
Quantifying Glomerular Filtration Rates in Acute Kidney Injury: A Requirement for Translational Success.
Review in Seminars in nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Renal safety of critical care sedation with sevoflurane: a systematic review and meta-analysis.Journal of anesthesia · 2023Pooled it
- Impact of continuous positive airway pressure therapy on metabolic and renal parameters in patients with obstructive sleep apnea, type 2 diabetes mellitus, and chronic kidney disease: a prospective cohort study.International urology and nephrology · 2026Article
- Comparison of kinetic and standard formulas for estimating glomerular filtration rate in acute kidney injury: implications for antibiotic dosing, a prospective study.European journal of clinical pharmacology · 2025Observational
- Effects of inpatient creatinine testing frequency on acute kidney injury identification and staging: a historical cohort study.International journal of clinical pharmacy · 2024Article
- Subcutaneous injection of adipose stromal cell-secretome improves renal function and reduces inflammation in established acute kidney injury.Stem cell research & therapy · 2024Article
- Evaluation of risk stratification for acute kidney injury: a comparative analysis of EKFC, 2009 and 2021 CKD-EPI glomerular filtration estimating equations.Journal of nephrology · 2024Observational
- Machine-learning enhancement of urine dipstick tests for chronic kidney disease detection.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- Data Analysis of Impaired Renal and Cardiac Function Using a Combination of Standard Classifiers.Journal of personalized medicine · 2023Article
- Use of Race in Kidney Function Estimation: Lessons Learned and the Path Toward Health Justice.Annual review of medicine · 2023Review
- Optimization of antimicrobial dosing in patients with acute kidney injury: a single-centre observational study.JAC-antimicrobial resistance · 2022Article
- Serum creatinine and cystatin C-based estimates of glomerular filtration rate are misleading in acute heart failure.ESC heart failure · 2021Article
- GFR estimation is complicated by a high incidence of non-steady-state serum creatinine concentrations at the emergency department.PloS one · 2021Article
- Observational
- Kinetic GFR Outperforms CKD-EPI for Slow Graft Function Prediction in the Immediate Postoperative Period Following Kidney Transplantation.Journal of clinical medicine · 2020Article
- Article
- Creatinine Fluctuations Forecast Cross-Harvest Kidney Function Decline Among Sugarcane Workers in Guatemala.Kidney international reports · 2020Article
- Acute Kidney Injury: A Frequently Underestimated Problem in Perioperative Medicine.Deutsches Arzteblatt international · 2019Review
- Molecular nephrology: types of acute tubular injury.Nature reviews. Nephrology · 2019Review
- Subclinical AKI: ready for primetime in clinical practice?Journal of nephrology · 2019Review
- Assessment of Regional Perfusion and Organ Function: Less and Non-invasive Techniques.Frontiers in medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Acute kidney injury (AKI) remains a vexing clinical problem that results in unacceptably high patient mortality, development of chronic kidney disease, and accelerated progression to end-stage kidney disease. Although clinical risks factors for developing AKI have been identified, there is no reasonable surveillance technique to definitively and rapidly diagnose and determine the extent of severity of AKI in any patient. Because patient outcomes correlate with the extent of injury, and effective therapy likely requires early intervention, the ability to rapidly diagnose and stratify patients by their level of kidney injury is paramount for translational progress. Many groups are developing and characterizing optical measurement techniques using novel minimally invasive or noninvasive techniques that can quantify kidney function independent of serum or urinary measurements. The use of both one- and two-compartment models, as well as continuous monitoring, are being developed. This review documents the need for glomerular filtration rate measurement in AKI patients and discusses the approaches being taken to deliver this overdue technique that is necessary to help propel nephrology to individualization of care and therapeutic success.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.