ArticleFunctional & integrative genomics2016
Genetic and physical mapping of the earliness per se locus Eps-A (m) 1 in Triticum monococcum identifies EARLY FLOWERING 3 (ELF3) as a candidate gene.
Article in Functional & integrative genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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63 citing papers in PubMed, 123 citations in OpenAlex.
- Metabolism in Sync: The Circadian Clock, a Central Hub for Light-Driven Chloroplastic and Mitochondrial Entrainment.Plants (Basel, Switzerland) · 2025Review
- Identification of novel candidate gene associated with early heading on chromosome 5B in wheat mutantMolecular breeding : new strategies in plant improvement · 2025Article
- Molecular genetic regulation of the vegetative-generative transition in wheat from an environmental perspective.Annals of botany · 2025Review
- Identification of robust yield quantitative trait loci derived from cultivated emmer for durum wheat improvement.The plant genome · 2025Article
- Genome-wide association study to identify the genomic loci associated with wheat heading date variation under autumn-sowing conditions.PloS one · 2025Article
- Breeding potential of Spanish bread wheat landraces: genetic variability in vernalization and photoperiod sensitivity.Frontiers in plant science · 2025Article
- An eight-founder wheat MAGIC population allows fine-mapping of flowering time loci and provides novel insights into the genetic control of flowering time.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Tracing the Evolutionary History of the Temperature-Sensing Prion-like Domain in EARLY FLOWERING 3 Highlights the Uniqueness of AtELF3.Molecular biology and evolution · 2024Article
- Delineation of loci governing an extra-earliness trait in lentil (Lens culinaris Medik.) using the QTL-Seq approach.Plant biotechnology journal · 2024Article
- Quantitative Trait Loci Mapping of Heading Date in Wheat under Phosphorus Stress Conditions.Genes · 2024Article
- LEAFY and WAPO1 jointly regulate spikelet number per spike and floret development in wheat.Development (Cambridge, England) · 2024Article
- Identification of the causal mutation in early heading mutant of bread wheat (Molecular breeding : new strategies in plant improvement · 2024Article
- Analysis of the Effects of thePlants (Basel, Switzerland) · 2024Article
- Phytochromes transmit photoperiod information via the evening complex in Brachypodium.Genome biology · 2023Article
- PHYTOCHROME C regulation of photoperiodic flowering via PHOTOPERIOD1 is mediated by EARLY FLOWERING 3 in Brachypodium distachyon.PLoS genetics · 2023Article
- EARLY FLOWERING 3 interactions with PHYTOCHROME B and PHOTOPERIOD1 are critical for the photoperiodic regulation of wheat heading time.PLoS genetics · 2023Article
- Wheat EARLY FLOWERING 3 affects heading date without disrupting circadian oscillations.Plant physiology · 2023Article
- A 'wiring diagram' for sink strength traits impacting wheat yield potential.Journal of experimental botany · 2023Review
- Article
- Altered regulation of flowering expands growth ranges and maximizes yields in major crops.Frontiers in plant science · 2023Review
3 more citing papers are in PubMed but not listed here.
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5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Wheat cultivars exposed to optimal photoperiod and vernalization treatments still exhibit differences in flowering time, referred to as earliness per se (Eps). We previously identified the Eps-A (m) 1 locus from Triticum monococcum and showed that the allele from cultivated accession DV92 significantly delays heading time and increases the number of spikelets per spike relative to the allele from wild accession G3116. Here, we expanded a high-density genetic and physical map of the Eps-A (m) 1 region and identified the wheat ortholog of circadian clock regulator EARLY FLOWERING 3 (ELF3) as a candidate gene. No differences in ELF3 transcript levels were found between near-isogenic lines carrying the DV92 and G3116 Eps-A (m) 1 alleles, but the encoded ELF3 proteins differed in four amino acids. These differences were associated with altered transcription profiles of PIF-like, PPD1, and FT1, which are known downstream targets of ELF3. Tetraploid wheat lines with combined truncation mutations in the A- and B-genome copies of ELF3 flowered earlier and had less spikelets per spike than the wild-type control under short- and long-day conditions. Both effects were stronger in a photoperiod-sensitive than in a reduced photoperiod-sensitive background, indicating a significant epistatic interaction between PPD1 and ELF3 (P < 0.0001). By contrast, the introgression of the T. monococcum chromosome segment carrying the Eps-A (m) 1 allele from DV92 into durum wheat delayed flowering and increased the number of spikelets per spike. Taken together, the above results support the hypothesis that ELF3 is Eps-A (m) 1. The ELF3 alleles identified here provide additional tools to modulate reproductive development in wheat.
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