ReviewKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2017
Do autologous blood transfusion systems reduce allogeneic blood transfusion in total knee arthroplasty?
Review in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Reduction of Blood Loss by Intra-articular Injection of Tranexamic Acid Combined with Knee and Hip Flexion at 45° During Primary Total Knee Arthroplasty: A Randomized Controlled Trial.Orthopaedic surgery · 2020Trial
- The Effect of Autologous Blood Transfusion in Open Heart Procedures on the Requirement of Allogeneic Blood Products.Cureus · 2025Article
- Vital signs following autotransfusion in liposuction and concurrent aesthetic procedures.Revista do Colegio Brasileiro de Cirurgioes · 2025Article
- Analysis of blood utilisation efficiency driven by clinical management and hospital heterogeneity.Frontiers in public health · 2025Article
- Development and validation of a nomogram for blood transfusion during intracranial aneurysm clamping surgery: a retrospective analysis.BMC medical informatics and decision making · 2023Article
- Risk factors analysis and nomogram construction for blood transfusion in elderly patients with femoral neck fractures undergoing hemiarthroplasty.International orthopaedics · 2022Article
- Intravenous Ferric Carboxymaltose Improves Response to Postoperative Anemia Following Total Knee Arthroplasty: A Prospective Randomized Controlled Trial in Asian Cohort.Journal of clinical medicine · 2022Article
- Article
- Transfusion of stored autologous blood in patients with low-grade pseudomyxoma peritonei: A retrospective analysis of its safety and outcome.Frontiers in oncology · 2022Article
- Serum Levels of VWF, t-PA, TNF-Genetics research · 2022Article
- Does Autologous Transfusion Decrease Allogeneic Transfusion in Liposuction Surgery of Lymphedema Patients?Frontiers in medicine · 2022Article
- Effects of stored autotransfusion on electrolytes and postoperative complications in patients undergoing elective orthopedic surgery.American journal of translational research · 2021Article
- Effects of Tranexamic Acid on Hemorrhage Control and Deep Venous Thrombosis Rate After Total Knee Arthroplasty: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.Frontiers in pharmacology · 2021Article
- Effectiveness of iron supplementation in the perioperative management of total knee arthroplasty: a systematic review.Knee surgery & related research · 2020Article
- Surgical vacuum filter-derived stromal cells are superior in proliferation to human bone marrow aspirate.Stem cell research & therapy · 2019Article
- Perioperative allogenic blood transfusion increases the incidence of postoperative deep vein thrombosis in total knee and hip arthroplasty.Journal of orthopaedic surgery and research · 2019Article
- Does blood transfusion type affect complication and length of stay following same-day bilateral total knee arthroplasty?Journal of orthopaedics · 2018Article
- No benefit of autologous transfusion drains in total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo study whether autologus blood transfusion systems reduce the requirement of allogneic blood transfusion in patients undergoing total knee arthroplasty.
methodsA comprehensive search of the published literature with PubMed, Scopus and Science direct database was performed. The following search terms were used: (total knee replacement) OR (total knee arthroplasty) OR (TKA) AND (blood transfusion) OR (autologous transfusion) OR (autologous transfusion system). Using search syntax, a total of 748 search results were obtained (79 from PubMed, 586 from Science direct and 83 from Scopus). Twenty-one randomized control trials were included for this meta-analysis.
resultsThe allogenic transfusion rate in autologus blood transfusion (study) group was significantly lower than the control group (28.4 and 53.5 %, respectively) (p value 0.0001, Relative risk: 0.5). The median units of allogenic blood transfused in study control group and control group were 0.1 (0.1-3.0) and 1.3 (0.3-2.6), respectively. The median hospital stay in study group was 9 (6.7-15.6) days and control group was 8.7 (6.6-16.7) days. The median cost incurred for blood transfusion per patient in study and control groups was 175 (85.7-260) and 254.7 (235-300) euros, respectively.
conclusionThis meta-analysis demonstrates that the use of auto-transfusion systems is a cost-effective method to reduce the need for and quantity of allogenic transfusion in elective total knee arthroplasty. LEVEL OF EVIDENCE: Level I.
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Identifiers
27085359What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.