Evidence map›Paper›PMID 27085338›Full record

Observational studyJournal of gastroenterology2017

A prospective, multicenter survey on the validity of shorter periendoscopic cessation of antithrombotic agents in Japan.

Katsuhiro Mabe, Mototsugu Kato, Koji Oba, Soichi Nakagawa, Hideyuki Seki, Shinichi Katsuki, Kentaro Yamashita, Shoko Ono, Yuichi Shimizu, Naoya Sakamoto and 1 more

Abstract readMulticenter StudyObservational StudyValidation Study
PubMed Publisher
In one paragraph

Observational study in Journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Recommendation Reversals in Gastroenterology Clinical Practice Guidelines.Journal of the Canadian Association of Gastroenterology · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Katsuhiro MabeDepartment of Gastroenterology, National Hospital Organization Hakodate Hospital, 18-16, Kawahara-cho, Hakodate City, Hokkaido, 041-8512, Japan. kmabe@hnh.hosp.go.jp.
Mototsugu KatoDivision of Endoscopy, Hokkaido University Hospital, Sapporo, Japan.
Koji ObaDepartment of Biostatistics, School of Public Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Soichi NakagawaNakagawa Ichoka-Clinic, Sapporo, Japan.
Hideyuki SekiCenter of Gastroenterology, KKR Sapporo Medical Center, Sapporo, Japan.
Shinichi KatsukiCenter of Gastroenterology, Otaru Ekisaikai Hospital, Otaru, Japan.
Kentaro YamashitaDepartment of Gastroenterology, Rheumatology and Clinical Immunology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Shoko OnoDivision of Endoscopy, Hokkaido University Hospital, Sapporo, Japan.
Yuichi ShimizuDepartment of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Naoya SakamotoDepartment of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Sapporo Consensus Study Group
Hokkaido University · JPHokkaido University Hospital · JPNTT Medical Center · JPSapporo Medical University · JPNational Hospital Organization · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of antithrombotic agents for endoscopic procedures has recently focused on preventing periprocedural thrombosis in Western countries. However, this focus on shorter cessation of antithrombotic agents needs to be examined for its implications for post-procedural bleeding, with potential risk factors for such bleeding clarified in real-world clinical settings in Japan.

methodsA Sapporo consensus group convened and developed a consensus document on the criteria for cessation of antithrombotic agents. In the multicenter, prospective, observational study that followed to validate the criteria in a real-world clinical setting, of all patients ≥20 years of age receiving antithrombotic agents and undergoing endoscopic procedures, all consenting patients were enrolled. All participating facilities were followed up on their adherence to the criteria and clinical outcomes, such as the occurrence of post-procedural bleeding and thrombosis.

resultsA total of 5250 patients, who accounted for 6944 endoscopic procedures, were enrolled from 19 study sites. The consensus criteria, which proved to be nearly consistent with the JSGE criteria revised in 2012, had been adhered to in a total of 6531 procedures performed in 4921 patients. Bleeding and thrombosis were reported in 53 (0.76 %) and two (0.03 %) patients, respectively, among those receiving antithrombotic agents. Post-procedural bleeding was significantly associated with high-bleeding-risk procedures, a high thromboembolic risk with heparin bridging, and the presence of renal failure/dialysis.

conclusionsWith the new criteria in place for cessation of antithrombotic agents focused on prevention of periprocedural thrombosis, endoscopic procedures may be safely performed without substantially increasing bleeding in clinical practice in Japan.

Indexed as

AdultAgedAged, 80 and overEndoscopyFemaleFibrinolytic AgentsHemorrhageHumansJapanMaleMiddle AgedProspective StudiesRisk FactorsThrombosisTime FactorsYoung AdultFibrinolytic AgentsBleedingCriteria for antithrombotic drug cessationEndoscopic proceduresManagement of antithrombotic agents

Identifiers

PMID27085338
OpenAlexW2335943421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.