Trial reportLasers in medical science2016
Effects of oral motor exercises and laser therapy on chronic temporomandibular disorders: a randomized study with follow-up.
Trial report in Lasers in medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 6 syntheses or guidelines pooled it, 96 citations in OpenAlex.
- Effectiveness of photobiomodulation and orofacial myofunctional therapy in orofacial pain disorders. A systematic review of randomized control trials.Lasers in medical science · 2024Pooled it
- Home-based rehabilitation versus centre-based programs in patients with temporomandibular disorders-a systematic review and meta-analysis.Journal of oral & facial pain and headache · 2024Pooled it
- Pooled it
- Rehabilitation strategies in maxillofacial trauma: systematic review and meta-analysis.Oral and maxillofacial surgery · 2020Pooled it
- Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis.Pain research & management · 2018Pooled it
- Low-level laser therapy in temporomandibular joint disorders: a systematic review.Journal of medicine and lifePooled it
- Effect of oral exercises and photobiomodulation therapy in the rehabilitation of patients with mandible fractures: randomized double-blind clinical trial.Lasers in medical science · 2022Trial
- Trial
- Trial
- Effect of photobiomodulation therapy on painful temporomandibular disorders.Scientific reports · 2021Trial
- Diagnosis-based pathways for conservative and minimally invasive management of temporomandibular disorders: a scoping review.Journal of oral & facial pain and headache · 2026Article
- Factors associated with orofacial myofunctional condition in patients with temporomandibular disorder and somatosensory tinnitus.Journal of applied oral science : revista FOB · 2026Observational
- The Effectiveness of Orofacial Myofunctional Therapy in Adults with Myogenous Temporomandibular Disorders: Insights from a Pilot Study.Journal of clinical medicine · 2025Article
- Photobiomodulation on vocal training and rehabilitation: Delphi consensus based on experts.CoDAS · 2025Article
- Anterior Disc Displacement of Temporomandibular Joint: Imaging Diagnosis and Multidisciplinary Treatment.International journal of general medicine · 2025Review
- Shedding light on Brazil's contribution to photobiomodulation research in oral medicine: a bibliometric study.Brazilian oral research · 2025Article
- Korean Medicine Clinical Practice Guideline Update for Temporomandibular Disorders: An Evidence-Based Approach.Healthcare (Basel, Switzerland) · 2023Article
- Web version of the protocol of the orofacial myofunctional evaluation with scores: usability and learning.CoDAS · 2023Article
- TNF-α levels and presence of SNP-308G/A of TNF-α gene in temporomandibular disorder patients.Dental press journal of orthodontics · 2022Review
- The Impact of Education and Physical Therapy on Oral Behaviour in Patients with Temporomandibular Disorder: A Preliminary Study.BioMed research international · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the efficacy of combining low-level laser therapy (LLLT) with oral motor exercises (OM-exercises) for rehabilitation of patients with chronic temporomandibular disorders (TMDs). Eighty-two patients with chronic TMD and 20 healthy subjects (control group) participated in the study. Patients were randomly assigned to treatment groups: GI (LLLT + OM exercises), GII (orofacial myofunctional therapy-OMT-which contains pain relief strategies and OM-exercises), and GIII (LLLT placebo + OM-exercises) and GIV (LLLT). LLLT (AsGaAl; 780-nm wavelength; average power of 60 mW, 40 s, and 60 ± 1.0 J/cm²) was used to promote analgesia, while OM-exercises were used to reestablish the orofacial functions. Evaluations at baseline (T1), after treatment immediate (T2), and at follow-up (T3) were muscle and joint tenderness to palpation, TMD severity, and orofacial myofunctional status. There was a significant improvement in outcome measures in all treated groups with stability at follow-up (Friedman test, P < 0.05), but GIV did not show difference in orofacial functions after LLLT (P > 0.05). Intergroup comparisons showed that all treated groups had no difference in tenderness to palpation of temporal muscle compared to GC at follow-up (Kruskal-Wallis test, P < 0.01). Moreover, GI, GII, and GIII showed no difference from GC in orofacial functional condition (T2 and T3) while they differed significantly from GIV (P < 0.01). In conclusion, LLLT combined with OM-exercises was more effective in promoting TMD rehabilitation than LLLT alone was. Similar treatment results were verified with the OMT protocol.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.