ArticleJournal of muscle research and cell motility1989
Identification and pattern of expression of a developmental isoform of troponin I in chicken and rat cardiac muscle.
Article in Journal of muscle research and cell motility, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed, 69 citations in OpenAlex.
- Sarcomere maturation: function acquisition, molecular mechanism, and interplay with other organelles.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine.Nature reviews. Cardiology · 2020Review
- Engineered Microenvironments for Maturation of Stem Cell Derived Cardiac Myocytes.Theranostics · 2018Review
- Engineering adolescence: maturation of human pluripotent stem cell-derived cardiomyocytes.Circulation research · 2014Review
- The effects of slow skeletal troponin I expression in the murine myocardium are influenced by development-related shifts in myosin heavy chain isoform.The Journal of physiology · 2012Article
- Expression and distribution of voltage-gated ion channels in ferret sinoatrial node.Physiological genomics · 2010Article
- Pathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations.Physiological genomics · 2010Article
- Enhanced proliferation of monolayer cultures of embryonic stem (ES) cell-derived cardiomyocytes following acute loss of retinoblastoma.PloS one · 2008Article
- Expression of slow skeletal myosin binding C-protein in normal adult mammalian heart.Journal of muscle research and cell motility · 2005Article
- Transient expression of fast troponin C transcripts in embryonic quail heart.Journal of muscle research and cell motility · 2005Article
- Developmental changes in contractility and sarcomeric proteins from the early embryonic to the adult stage in the mouse heart.The Journal of physiology · 2003Article
- Slow troponin T mRNA in striated muscles is expressed in both cell type and developmental stage specific manner.Journal of muscle research and cell motility · 2000Article
- Development and composition of skeletal muscle fibres in mouse oesophagus.Journal of muscle research and cell motility · 2000Article
- Troponin I: inhibitor or facilitator.Molecular and cellular biochemistry · 1999Review
- Assembly of force-expressed troponin-I isoforms in myofibrils of cultured cardiac and fast skeletal muscle cells as studied by epitope tagging.Journal of muscle research and cell motility · 1998Article
- Regulation of the rat cardiac troponin I gene by the transcription factor GATA-4.The Biochemical journal · 1997Article
- Strong evolutionary conservation of broadly expressed protein isoforms in the troponin I gene family and other vertebrate gene families.Journal of molecular evolution · 1996Article
- Role of regulatory proteins (troponin-tropomyosin) in pathologic states.Molecular and cellular biochemistry · 1994Review
- Forced expression and assembly of rat cardiac troponin T isoforms in cultured muscle and nonmuscle cells.Journal of muscle research and cell motility · 1993Article
- Protein kinase C phosphorylation of cardiac troponin T decreases Ca(2+)-dependent actomyosin MgATPase activity and troponin T binding to tropomyosin-F-actin complex.The Biochemical journal · 1992Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A monoclonal antibody that reacts with all known isoforms of troponin I detected a single isoform of cardiac troponin I in both atrial and ventricular chambers of adult chicken and rat hearts in an immunoblotting analysis. Another isoform of troponin I in addition to the adult cardiac form, however, was present in all chambers of the heart during early development in both species. This developmental isoform appeared to have the same electrophoretic mobility on SDS tris glycine polyacrylamide gels as that observed for the adult slow skeletal muscle isoform. In the rat, only the developmental isoform of troponin I was present in the early foetal heart and small amounts of the adult cardiac isoform were not apparent until late in gestation, whereas the developmental and adult isoforms were expressed in approximately equal amounts throughout embryonic development in the chicken. The level of developmental isoform of troponin I in both the chicken and the rat hearts gradually decreased so that only small amounts of this variant were detectable two weeks after birth or post hatching.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.