Evidence map›Paper›PMID 27084944›Full record

ArticleNucleic acids research2016

MBROLE 2.0-functional enrichment of chemical compounds.

Javier López-Ibáñez, Florencio Pazos, Mónica Chagoyen

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 1 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 1 synthesis or guideline pooled it, 216 citations in OpenAlex.

  1. Pooled it
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  10. Long-Term Elevated COAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Javier López-IbáñezComputational Systems Biology Group, National Centre for Biotechnology (CNB-CSIC), Madrid 28049, Spain.
Florencio PazosComputational Systems Biology Group, National Centre for Biotechnology (CNB-CSIC), Madrid 28049, Spain.
Mónica ChagoyenComputational Systems Biology Group, National Centre for Biotechnology (CNB-CSIC), Madrid 28049, Spain monica.chagoyen@cnb.csic.es.
Centro Nacional de Biotecnología · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolites Biological Role (MBROLE) is a server that performs functional enrichment analysis of a list of chemical compounds derived from a metabolomics experiment, which allows this list to be interpreted in biological terms. Since its release in 2011, MBROLE has been used by different groups worldwide to analyse metabolomics experiments from a variety of organisms. Here we present the latest version of the system, MBROLE2, accessible at http://csbg.cnb.csic.es/mbrole2 MBROLE2 has been supplemented with 10 databases not available in the previous version, which allow analysis over a larger, richer set of vocabularies including metabolite-protein and drug-protein interactions. This new version performs automatic conversion of compound identifiers from different databases, thus simplifying usage. In addition, the user interface has been redesigned to generate an interactive, more intuitive representation of the results.

Indexed as

MetabolomicsUser-Computer InterfaceActinobacteriaAnimalsArecaceaeComputer GraphicsCordycepsDatabases, ChemicalDatabases, GeneticEscherichia coliHumansInternetMetabolic Networks and PathwaysRatsSmall Molecule LibrariesSynechococcusSmall Molecule Libraries

Identifiers

PMID27084944
PMCPMC4987872
OpenAlexW2342061641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.