Evidence map›Paper›PMID 27084749›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2017

Economic impact of patients admitted to stroke units in Spain.

Jose Alvarez-Sabín, Manuel Quintana, Jaime Masjuan, Juan Oliva-Moreno, Javier Mar, Nuria Gonzalez-Rojas, Virginia Becerra, Covadonga Torres, María Yebenes, CONOCES Investigators Group

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07627399 (Effectiveness of Implementing Best Care Practices in the Management of Patients With Acute Stroke in Conventional Hospitalization), which is not on this map. Cited by 40 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07627399 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effectiveness of Implementing Best Care Practices in the Management of Patients With Acute Stroke in Conventional Hospitalization: A Cluster-Randomized, Open, Stepped-Wedge Controlled Trial.

TypeinterventionalSponsorUniversity of MalagaRan2026 to 2028Enrolled700ConditionsStroke, Acute Stroke, Ischemic Stroke, Hemorrhagic StrokeArmsBEST CARE ICTUS_HC BUNDLE
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Economic Burden of Stroke Disease: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  7. Pooled it
  8. Pooled it
  9. Early Occupational Therapy Intervention in the Hospital Discharge after Stroke.International journal of environmental research and public health · 2021
    Trial
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. The budget impact of implementing atrial fibrillation-screening in European countries.European heart journal supplements : journal of the European Society of Cardiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jose Alvarez-SabínServei de Neurologia, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron 119-129, 08035, Barcelona, Spain. josalvarez@vhebron.net.
Manuel QuintanaServei de Neurologia, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron 119-129, 08035, Barcelona, Spain.
Jaime MasjuanStroke Unit, Department of Neurology, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Madrid, Spain.
Juan Oliva-MorenoDepartment of Economic Analysis, Universidad de Castilla La Mancha and REDISSEC, Toledo, Spain.
Javier MarClinical Management Service, Hospital Alto Deba, Mondragon, Spain.
Nuria Gonzalez-RojasHealth Economics and Outcomes Research, Boehringer Ingelheim España, Barcelona, Spain.
Virginia BecerraHealth Economics and Outcomes Research, Boehringer Ingelheim España, Barcelona, Spain.
Covadonga TorresPharmacoeconomics and Outcomes Research Iberia, Madrid, Spain.
María YebenesPharmacoeconomics and Outcomes Research Iberia, Madrid, Spain.
CONOCES Investigators Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesStroke is a major social and health problem. However, since the recent incorporation of new advances in its management, little is known about the cost of stroke. The aim of this study is to find out the real cost of stroke in Spain.

methodsThis is an epidemiological, observational, prospective, multicenter study of patients diagnosed with stroke and admitted to a stroke unit. Patients were recruited from 16 hospitals throughout Spain and followed up for 1 year. Sociodemographic, clinical, and economic data were collected. Costs (€ 2012) were estimated from the social perspective and were divided into direct healthcare (inpatient, outpatient, and medication), direct non-healthcare (mainly formal and informal care) and labor productivity losses.

resultsA total of 321 patients were included. Mean age was 72.1 years and 176 patients (54.8 %) were male. Total average cost per patient/year was €27,711. Direct healthcare costs amounted to €8491 per patient/year (68.8 % due to inpatient costs) and non-healthcare costs to an average of €18,643 per patient/year (89.5 % due to informal care). Productivity loss costs per patient/year were €276. Total costs of hemorrhagic strokes were slightly higher than ischemic (€28,895 vs. €27,569 per patient/year, p = 0.550) without significant differences. The main variables associated with higher costs were the presence of hypertension (€30,332 vs. €23,234 per patient/year, p < 0.05) and the severity of stroke (p < 0.05), both independently associated after a multivariate analysis.

conclusionsThe cost of patients admitted to stroke units in Spain is €27,711 per patient/year. More than two-thirds are social costs, mainly informal care. Stroke remains a major burden on health systems and society, so additional efforts are needed for its prevention.

Indexed as

Cost of IllnessHealth Care CostsAgedAged, 80 and overComorbidityFemaleHospitalizationHospitalsHumansLinear ModelsMaleMiddle AgedPatient CareProspective StudiesSocial WorkSpainCost of illnessEconomic impactHealthcare and non-healthcare costsSocial perspectiveStroke

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.