Evidence map›Paper›PMID 27084374›Full record

ArticleRheumatology international2017

The metabolic profile in early rheumatoid arthritis: a high prevalence of metabolic obesity.

Raili Müller, Mart Kull, Kaja Põlluste, Annika Aart, Triin Eglit, Margus Lember, Riina Kallikorm

Abstract read
PubMed Publisher
In one paragraph

Article in Rheumatology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Atherosclerosis in Rheumatoid Arthritis: Promoters and Opponents.Clinical reviews in allergy & immunology · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Role of Inflammatory Diseases in Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2017
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raili MüllerDepartment of Internal Medicine, University of Tartu, L. Puusepa 8, 51014, Tartu, Estonia. raili.muller@kliinikum.ee.
Mart KullDepartment of Internal Medicine, University of Tartu, L. Puusepa 8, 51014, Tartu, Estonia.
Kaja PõllusteDepartment of Internal Medicine, University of Tartu, L. Puusepa 8, 51014, Tartu, Estonia.
Annika AartDepartment of Internal Medicine, University of Tartu, L. Puusepa 8, 51014, Tartu, Estonia.
Triin EglitDepartment of Internal Medicine, University of Tartu, L. Puusepa 8, 51014, Tartu, Estonia.
Margus LemberDepartment of Internal Medicine, University of Tartu, L. Puusepa 8, 51014, Tartu, Estonia.
Riina KallikormDepartment of Internal Medicine, University of Tartu, L. Puusepa 8, 51014, Tartu, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to compare the prevalence of metabolic syndrome (MetS) in early RA patients with age-gender-matched population controls focusing on the presence of MetS in different weight categories. The study group consisted of 91 consecutive patients with early RA and 273 age- and gender-matched controls subjects. MetS was diagnosed according to the National Cholesterol Education Program (NCEP-ATP III) criteria. Mean age in both groups was 52 years, and 72.5 % were female. The prevalence of MetS did not differ between the two groups (35.2 % in RA, 34.1 % in control group). Mean systolic blood pressure in the RA group was 137 mmHg, in control group 131 mmHg, P = 0.01, and diastolic blood pressure 85 versus 81 mmHg, respectively (P < 0.01). We found that 20 of 65 (30.8 %) of RA patients compared to 80 of 152 (52.6 %) of the control subjects with elevated blood pressure received antihypertensive treatment (P < 0.01). When comparing subgroups with normal BMI, the odds of having MetS (being metabolically obese) were higher among early RA subjects (OR 5.6, CI 1.3-23.8). Of the individual components of metabolic syndrome, we found increased prevalence of hypertension (OR 2.8, CI 1.3-6.0) and hyperglycemia (OR 2.9, CI 1.0-8.0) in the RA group. Recognition of abnormal metabolic status among normal-weight RA patients who have not yet developed CVD could provide a valuable opportunity for preventative intervention.

Indexed as

AdultAgedArthritis, RheumatoidBlood PressureComorbidityCross-Sectional StudiesDisease ProgressionFemaleHumansMaleMetabolic SyndromeMiddle AgedObesityPrevalenceEarly arthritisMetabolic obesityMetabolic syndromeRheumatoid arthritis

Identifiers

PMID27084374

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.