ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2016
Serum prolidase activity and oxidative stress in patients with pseudoexfoliation syndrome.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Comparison of serum iron, zinc and magnesium levels in pseudoexfoliation syndrome and pseudoexfoliation glaucoma: a case-control study.BMC ophthalmology · 2026Article
- Changes in the Protein Composition of the Aqueous Humor in Patients with Glaucoma: An Update Review.International journal of molecular sciences · 2025Review
- Aqueous humor and serum levels of 4-hydroxynonenal and 8-hydroxy-2'deoxyguanosine in pseudoexfoliation syndrome and glaucoma.International ophthalmology · 2023Article
- Antioxidant Defense and Pseudoexfoliation Syndrome: An Updated Review.Medical sciences (Basel, Switzerland) · 2022Review
- Emerging roles of oxidative stress in the pathogenesis of pseudoexfoliation syndrome (Review).Experimental and therapeutic medicine · 2022Review
- Sectorwise analysis of peripapillary vessel density and retinal nerve fiber layer thickness in exfoliation syndrome.International ophthalmology · 2021Article
- Evaluation of the optic nerve head vessel density in the patients with asymmetric pseudoexfoliative glaucoma: an OCT angiography study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
- Role of Oxidative Stress in Pseudoexfoliation Syndrome and Pseudoexfoliation GlaucomaTurkish journal of ophthalmology · 2019Article
- The Association of Oxidative Stress Status with Open-Angle Glaucoma and Exfoliation Glaucoma: A Systematic Review and Meta-Analysis.Journal of ophthalmology · 2019Review
- Growth Factors, Oxidative Damage, and Inflammation in Exfoliation Syndrome.Journal of glaucoma · 2018Review
- Decorin, Tenascin C, Total Antioxidant, and Total Oxidant Level Changes in Patients with Pseudoexfoliation Syndrome.Journal of ophthalmology · 2018Article
- Optical Coherence Tomography Angiography Vessel Density in Healthy, Pseudoexfoliation Syndrome and Exfoliative Glaucoma: Diagnostic Accuracy and Relationship with Structural Parameters.Journal of current ophthalmologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to evaluate the serum prolidase activity (SPA), malondialdehyde (MDA), and catalase levels in patients with pseudoexfoliation (PEX) syndrome.
methodThirty-four patients with PEX syndrome and thirty-eight age- and gender-matched healthy subjects were included in this prospective clinical study. Each participant underwent full ophthalmologic examination. The SPA, serum MDA, and catalase levels were measured and compared between the patients with PEX syndrome and healthy subjects.
resultsThe SPA was significantly lower in patients with PEX syndrome compared to healthy controls (14.1 ± 7.1 vs. 30.1 ± 4.3 ng/ml; p = 0.001). The mean serum MDA values the of PEX syndrome and control groups were comparable (28.7 ± 5.7 vs. 30.4 ± 5.3 nmol/ml, respectively; p = 0.185). The mean serum catalase level tended to be lower in the PEX group compared to healthy controls (0.12 ± 0.02 vs. 0.21 ± 0.05 k/ml, respectively; p = 0.077).
conclusionOur findings suggest that the SPA was significantly lower in patients with PEX syndrome compared to healthy controls. Thus, prolidase may have a role in the pathogenesis of the PEX syndrome.
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Registered trials
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