ReviewApplied and environmental microbiology2016
Symbiotic Nitrogen Fixation and the Challenges to Its Extension to Nonlegumes.
Review in Applied and environmental microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 174 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
174 citing papers in PubMed.
- Metagenomic analysis of rhizosphere soil microbiota in wild and cultivated Notopterygium incisum, an umbelliferae medicinal herb.BMC microbiology · 2026Article
- Review
- Response of nitrogen-fixing plant symbioses to changing temperature.Journal of integrative plant biology · 2026Review
- Bag-controlled low-nitrogen fertilization induces root arbutin secretion to enrich rhizosphere Pseudomonas and enhance nitrogen fixation in peach.Plant communications · 2026Article
- Spatiotemporal dynamics of ethylene biosynthesis shape infection and nodule initiation in Medicago truncatula.The Plant cell · 2026Article
- Nitrogenase regulation inbioRxiv : the preprint server for biology · 2026Article
- Engineering Symbiotic Nitrogen Fixation for Agriculture: Predominant Role of Host Plants and Fine-Tuning Regulation.Plants (Basel, Switzerland) · 2026Article
- Symbiosis-associated UMAMIT transporters required for establishing efficient nitrogen fixation in Medicago truncatula.The New phytologist · 2026Article
- Harnessing Nitrogen-Fixing and Phosphate-Mobilizing Bacteria for Sustainable Agriculture.Microorganisms · 2026Review
- Divergence in the tomato rhizosphere microbial community structure driven by three soil types.Microbiology spectrum · 2026Article
- Bacterial Strains from Soybean Nodules in the Lower Volga Region Belong to a New SubspeciesMicroorganisms · 2026Article
- Developing improved inoculants through genome editing of diazotrophic bacteria for cereals: Is this the right time for Brazil?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Harnessing Silicon and Nanosilicon Formulations withInternational journal of molecular sciences · 2026Review
- Enhancement of Nitrogenase Activity in Recombinant Escherichia coli by Replacing Upstream Region of nif Operon from Paenibacillus Species.Chembiochem : a European journal of chemical biology · 2026Article
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- Mutations in legume genes that influence symbiosis create a complex selective landscape for rhizobial symbionts.The ISME journal · 2026Article
- Microbial Biotechnology in Agriculture.Progress in molecular and subcellular biology · 2026Review
- Development of molecular biomarkers for monitoring of arable crops colonization withFrontiers in plant science · 2026Article
- Rhizosphere microbiome dynamics and plant adaptation to abiotic stress in major oilseed crops: a review.Frontiers in plant science · 2026Review
- Ecological constraints and evolutionary trade-offs shape nitrogen fixation across habitats.ISME communications · 2026Article
114 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
Access to fixed or available forms of nitrogen limits the productivity of crop plants and thus food production. Nitrogenous fertilizer production currently represents a significant expense for the efficient growth of various crops in the developed world. There are significant potential gains to be had from reducing dependence on nitrogenous fertilizers in agriculture in the developed world and in developing countries, and there is significant interest in research on biological nitrogen fixation and prospects for increasing its importance in an agricultural setting. Biological nitrogen fixation is the conversion of atmospheric N2 to NH3, a form that can be used by plants. However, the process is restricted to bacteria and archaea and does not occur in eukaryotes. Symbiotic nitrogen fixation is part of a mutualistic relationship in which plants provide a niche and fixed carbon to bacteria in exchange for fixed nitrogen. This process is restricted mainly to legumes in agricultural systems, and there is considerable interest in exploring whether similar symbioses can be developed in nonlegumes, which produce the bulk of human food. We are at a juncture at which the fundamental understanding of biological nitrogen fixation has matured to a level that we can think about engineering symbiotic relationships using synthetic biology approaches. This minireview highlights the fundamental advances in our understanding of biological nitrogen fixation in the context of a blueprint for expanding symbiotic nitrogen fixation to a greater diversity of crop plants through synthetic biology.
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