Evidence map›Paper›PMID 27083925›Full record

ReviewSeminars in immunopathology2016

TRP functions in the broncho-pulmonary system.

Francesco De Logu, Riccardo Patacchini, Giovanni Fontana, Pierangelo Geppetti

Abstract readReview
PubMed Publisher
In one paragraph

Review in Seminars in immunopathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Ion Channels in the Immune Response of Asthma.Journal of respiratory biology and translational medicine · 2024
    Article
  6. Article
  7. Article
  8. Inflammation-the role of TRPA1 channel.Frontiers in physiology · 2023
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. TRP channels in airway sensory nerves.Neuroscience letters · 2021
    Review
  15. Review
  16. Article
  17. A distinct structural mechanism underlies TRPV1 activation by piperine.Biochemical and biophysical research communications · 2019
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Francesco De LoguClinical Pharmacology Unit, Department of Health Sciences, University of Florence, Viale Pieraccini, 6, 50139, Florence, Italy.
Riccardo PatacchiniClinical Pharmacology Unit, Department of Health Sciences, University of Florence, Viale Pieraccini, 6, 50139, Florence, Italy.
Giovanni FontanaDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Pierangelo GeppettiClinical Pharmacology Unit, Department of Health Sciences, University of Florence, Viale Pieraccini, 6, 50139, Florence, Italy. pierangelo.geppetti@unifi.it.
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current understanding of the role of transient receptor potential (TRP) channels in the airways and lung was initially based on the localization of a series of such channels in a subset of sensory nerve fibers of the respiratory tract. Soon after, TRP channel expression and function have been identified in respiratory nonneuronal cells. In these two locations, TRPs regulate physiological processes aimed at integrating different stimuli to maintain homeostasis and to react to harmful agents and tissue injury by building up inflammatory responses and repair processes. There is no doubt that TRPs localized in the sensory network contribute to airway neurogenic inflammation, and emerging evidence underlines the role of nonneuronal TRPs in orchestrating inflammation and repair in the respiratory tract. However, recent basic and clinical studies have offered clues regarding the contribution of neuronal and nonneuronal TRPs in the mechanism of asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, cough, and other respiratory diseases.

Indexed as

Respiratory Physiological PhenomenaAnimalsAsthmaDisease SusceptibilityGene ExpressionHumansMultigene FamilyProtein IsoformsPulmonary Disease, Chronic ObstructiveRespiratory SystemSensory Receptor CellsTransient Receptor Potential ChannelsProtein IsoformsTransient Receptor Potential ChannelsNeurogenic inflammationOxidative stressTRPA1TRPV1

Identifiers

PMID27083925
OpenAlexW2341598415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.