ReviewJournal of neurology2016
Vestibular paroxysmia: a treatable neurovascular cross-compression syndrome.
Review in Journal of neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 103 citations in OpenAlex.
- Vestibular paroxysmia: a systematic review.Journal of neurology · 2025Pooled it
- The Association of Vascular Loops within the Internal Auditory Meatus or Contacting the Vestibulo-Cochlear Nerve with Audiovestibular Symptoms: A Systematic Review and Meta-Analysis.AJNR. American journal of neuroradiology · 2025Pooled it
- Classification of vestibular signs and examination techniques: Nystagmus and nystagmus-like movements.Journal of vestibular research : equilibrium & orientationGuideline
- Randomized trial of betahistine mesilate tablets as augmentation for oxcarbazepine and carbamazepine in treating vestibular paroxysmia.Drug design, development and therapy · 2018Trial
- Vestibular Paroxysmia Coexisting With Meige Syndrome: A Case Report.Clinical case reports · 2026Article
- Vestibular Paroxysmia Presenting With Atypical Positional Nystagmus Resembling Benign Paroxysmal Positional Vertigo.Journal of general and family medicine · 2026Article
- [The SCD diagnostic strategy, procedure and pathway for episodic vestibular syndrome].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026Review
- [Study on the characteristics of magnetic resonance hydrography of the inner ear in patients with total deafness-type sudden sensorineural hearing loss].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026Article
- Article
- Trigeminal Nerve and Vestibular System: Update on Pathophysiological and Clinical Links.Audiology research · 2025Review
- Article
- Vestibular Paroxysmia with Neurovascular Cross Compression and Antiepileptic Drugs: A Systematic Review and Discussion of Physiopathology.Audiology research · 2025Review
- Medical Management of the Near-Narrowed Internal Auditory Canal Pathology in the Adult Population: A Preliminary Study.Journal of clinical medicine · 2025Article
- World-wide survey on the treatment of peripheral vestibular disorders.Frontiers in neurology · 2025Article
- Head Shaking Nystagmus & Vertigo - Multiple Sclerosis or Vestibular Paroxysmia - A Diagnostic Dilemma.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Radiological and intraoperative findings of a rare case of vestibular paroxysmia.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Vestibular Paroxysmia: A Four-Case Report.Cureus · 2024Article
- The "Near"-Narrowed Internal Auditory Canal Syndrome in Adults: Clinical Aspects, Audio-Vestibular Findings, and Radiological Criteria for Diagnosis.Journal of clinical medicine · 2023Article
- Vestibular paroxysmia associated with congenital vascular malformation: A case report.Frontiers in neuroscience · 2023Article
- Application of ABR in pathogenic neurovascular compression of the 8th cranial nerve in vestibular paroxysmia.Acta neurochirurgica · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The leading symptoms of vestibular paroxysmia (VP) are recurrent, spontaneous, short attacks of spinning or non-spinning vertigo that generally last less than one minute and occur in a series of up to 30 or more per day. VP may manifest when arteries in the cerebellar pontine angle cause a segmental, pressure-induced dysfunction of the eighth nerve. The symptoms are usually triggered by direct pulsatile compression with ephaptic discharges, less often by conduction blocks. MR imaging reveals the neurovascular compression of the eighth nerve (3D constructive interference in steady state and 3D time-of-flight sequences) in more than 95% of cases. A loop of the anterior inferior cerebellar artery seems to be most often involved, less so the posterior inferior cerebellar artery, the vertebral artery, or a vein. The frequent attacks of vertigo respond to carbamazepine or oxcarbazepine, even in low dosages (200-600 mg/d or 300-900 mg/d, respectively), which have been shown to also be effective in children. Alternative drugs to try are lamotrigine, phenytoin, gabapentin, topiramate or baclofen or other non-antiepileptic drugs used in trigeminal neuralgia. The results of ongoing randomized placebo-controlled treatment studies, however, are not yet available. Surgical microvascular decompression of the eighth nerve is the "ultima ratio" for medically intractable cases or in exceptional cases of non-vascular compression of the eighth nerve by a tumor or cyst. The International Barany Society for Neuro-Otology is currently working on a consensus document on the clinical criteria for establishing a diagnosis of VP as a clinical entity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.