Evidence map›Paper›PMID 27083500›Full record

ReviewBehavioural processes2016

Determinants of choice, and vulnerability and recovery in addiction.

R J Lamb, David R Maguire, Brett C Ginsburg, Jonathan W Pinkston, Charles P France

Open access · greenAbstract readReview
In one paragraph

Review in Behavioural processes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Implications of there being many paths to addiction and recovery.Pharmacology, biochemistry, and behavior · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Addiction as a BAD, a Behavioral Allocation Disorder.Pharmacology, biochemistry, and behavior · 2018
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

R J LambUniversity of Texas Health Science Center at San Antonio, Department of Psychiatry, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, United States; University of Texas Health Science Center at San Antonio, Departments of Pharmacology, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, United States. Electronic address: lamb@uthscsa.edu.
David R MaguireUniversity of Texas Health Science Center at San Antonio, Departments of Pharmacology, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, United States. Electronic address: MaguireD@uthscsa.edu.
Brett C GinsburgUniversity of Texas Health Science Center at San Antonio, Department of Psychiatry, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, United States; University of Texas Health Science Center at San Antonio, Departments of Pharmacology, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, United States. Electronic address: Ginsburg@uthscsa.edu.
Jonathan W PinkstonUniversity of Texas Health Science Center at San Antonio, Department of Psychiatry, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, United States; University of North Texas, Department of Behavioral Analysis, 360 G Chilton Hall, Avenue C, Denton TX 76208, United States. Electronic address: Jonathan.Pinkston@unt.edu.
Charles P FranceUniversity of Texas Health Science Center at San Antonio, Department of Psychiatry, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, United States; University of Texas Health Science Center at San Antonio, Departments of Pharmacology, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, United States. Electronic address: France@uthscsa.edu.
The University of Texas Health Science Center at San Antonio · US

Funding

Training in Drug Abuse Research: Behavior and NeurobiologyT32DA031115 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHARLES P FRANCE · 2011 to 2026
$5.2M
Rat ethanol self-administration: respondent instrumental interactionsR01AA012337 · NIAAA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LAMB, RICHARD J · 2001 to 2016
$3.4M
Delay discounting: effects of drug dependence and withdrawalR01DA029254 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FRANCE, CHARLES P · 2010 to 2014
$1.4M
Behavioral Pharmacology of Drug DependenceK05DA017918 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FRANCE, CHARLES P · 2005 to 2014
$1.2M
Reinstatement of drug-maintained behavior suppressed by extinction or an availablR01AA016987 · NIAAA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI GINSBURG, BRETT C · 2008 to 2011
$790k
NIAAA NIH HHS R01 AA012337NIAAA NIH HHS R01 AA016987NIDA NIH HHS K05 DA017918NIDA NIH HHS R01 DA029254NIDA NIH HHS T32 DA031115
6 · The paper itself

Abstract

Addiction may be viewed as choice governed by competing contingencies. One factor impacting choice, particularly as it relates to addiction, is sensitivity to delayed rewards. Discounting of delayed rewards influences addiction vulnerability because of competition between relatively immediate gains of drug use, e.g. intoxication, versus relatively remote gains of abstinence, e.g. family stability. Factors modifying delay sensitivity can be modeled in the laboratory. For instance, increased delay sensitivity can be similarly observed in adolescent humans and non-human animals. Similarly, genetic factors influence delay sensitivity in humans and animals. Recovery from addiction may also be viewed as choice behavior. Thus, reinforcing alternative behavior facilitates recovery because reinforcing alternative behavior decreases the frequency of using drugs. How reinforcing alternative behavior influences recovery can also be modeled in the laboratory. For instance, relapse risk decreases as abstinence duration increases, and this decreasing risk can be modeled in animals using choice procedures. In summary, addiction in many respects can be conceptualized as a problem of choice. Animal models of choice disorders stand to increase our understanding of the core processes that establish and maintain addiction and serve as a proving ground for development of novel treatments.

Indexed as

Choice BehaviorDelay DiscountingAnimalsHumansReinforcement, PsychologySubstance-Related DisordersDelay discountingDifferential reinforcement of alternative behaviorRecoveryVulnerability

Identifiers

PMID27083500
PMCPMC4968700
OpenAlexW2339125300

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.