Evidence map›Paper›PMID 27082879›Full record

Observational studyPLoS neglected tropical diseases2016

Leprosy on Reunion Island, 2005-2013: Situation and Perspectives.

Guillaume Camuset, Sophie Lafarge, Gianandrea Borgherini, Anne Gerber, Nicolas Pouderoux, Aurélie Foucher, Patrice Poubeau, Rodolphe Manaquin, Sophie Larrieu, Pascal Vilain and 1 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Guillaume CamusetCentre Hospitalier Universitaire de la Réunion, Department of Infectious Disease, Saint-Pierre, France.
Sophie LafargeCentre Hospitalier Universitaire de la Réunion, INSERM, CIC 1410, Saint-Pierre, France.
Gianandrea BorgheriniCentre Hospitalier Universitaire de la Réunion, Department of Infectious Disease, Saint-Pierre, France.
Anne GerberCentre Hospitalier Universitaire de la Réunion, Department of Internal Medicine, Saint-Denis, France.
Nicolas PouderouxCentre de Lutte Anti-tuberculeuse Nord et Est, Saint-Denis, France.
Aurélie FoucherCentre Hospitalier Universitaire de la Réunion, Department of Infectious Disease, Saint-Pierre, France.
Patrice PoubeauCentre Hospitalier Universitaire de la Réunion, Department of Infectious Disease, Saint-Pierre, France.
Rodolphe ManaquinCentre Hospitalier Universitaire de la Réunion, Department of Infectious Disease, Saint-Pierre, France.
Sophie LarrieuRegional Office of French Institute for Public Health Surveillance of Indian Ocean, Saint-Denis, France.
Pascal VilainRegional Office of French Institute for Public Health Surveillance of Indian Ocean, Saint-Denis, France.
Laetitita HuiartCentre Hospitalier Universitaire de la Réunion, INSERM, CIC 1410, Saint-Pierre, France.
Centre Hospitalier Universitaire de La Réunion · FRInserm · FRInstitut de Veille Sanitaire · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReunion Island is a French overseas territory located in the south-western of Indian Ocean, 700 km east of Madagascar. Leprosy first arrived on Reunion Island in the early 1700s with the African slaves and immigration from Madagascar. The disease was endemic until 1980 but improvement of health care and life conditions of inhabitants in the island have allowed a strong decrease in new cases of leprosy. However, the reintroduction of the disease by migrants from endemic neighbouring countries like Comoros and Madagascar is a real and continuing risk. This observational study was then conducted to measure the number of new cases detected annually on Reunion Island between 2005 and 2013, and to describe the clinical features of these patients. METHODOLOGY/PRINCIPAL

findingsData were collected over two distinct periods. Incident cases between 2005 and 2010 come from a retrospective study conducted in 2010 by the regional Office of French Institute for Public Health Surveillance (CIRE of Indian Ocean), when no surveillance system exist. Cases between 2011 and 2013 come from a prospective collection of all new cases, following the implementation of systematic notification of all new cases. All patient data were anonymized. Among the 25 new cases, 12 are Reunion Island residents who never lived outside Reunion Island, and hence are considered to be confirmed autochthonous patients. Registered prevalence in 2014 was 0.05 /10 000 habitants, less than the WHO's eradication goal (1/10 000). CONCLUSIONS/SIGNIFICANCE: Leprosy is no longer a major public health problem on Reunion Island, as its low prevalence rate indicates. However, the risk of recrudescence of the disease and of renewed autochthonous transmission remains real. In this context, active case detection must be pursued through the active declaration and rapid treatment of all new cases.

Indexed as

AdolescentAdultAgedChildFemaleHumansIncidenceLeprosyMaleMiddle AgedProspective StudiesRetrospective StudiesReunionYoung Adult

Identifiers

PMID27082879
PMCPMC4833340
OpenAlexW2340850394

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.