Evidence map›Paper›PMID 27082749›Full record

SynthesisPloS one2016

The Mental Health of People Living with HIV in China, 1998-2014: A Systematic Review.

Lu Niu, Dan Luo, Ying Liu, Vincent M B Silenzio, Shuiyuan Xiao

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07080138 (Research on the Psychological Status of Patients With HIV-1 Infection), which is not on this map. Cited by 76 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07080138 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Research on the Psychological Status of Patients With HIV-1 Infection

TypeobservationalSponsorShanxi Bethune HospitalRan2025 to 2026Enrolled500ConditionsHIV-1-infection, Anxiety DepressionArmsAll kinds of INSTI medications, All kinds of conventional medications
3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lu NiuDepartment of Social Medicine and Health Management, School of Public Health, Central South University, Changsha, China.
Dan LuoDepartment of Social Medicine and Health Management, School of Public Health, Central South University, Changsha, China.
Ying LiuDepartment of Social Medicine and Health Management, School of Public Health, Central South University, Changsha, China.
Vincent M B SilenzioDepartment of Psychiatry, University of Rochester Medical Center, Rochester, New York, United States of America.
Shuiyuan XiaoDepartment of Social Medicine and Health Management, School of Public Health, Central South University, Changsha, China.

Funding

Virology/Immunology CoreP30AI078498 · NIAID · UNIVERSITY OF ROCHESTER · PI DEWHURST, STEPHEN · 2008 to 2018
$14.6M
China-Rochester Suicide Research Training Program (CRSRT)D43TW009101 · FIC · UNIVERSITY OF ROCHESTER · PI CAINE, ERIC D. · 2011 to 2015
$1.2M
FIC NIH HHS D43 TW009101NIAID NIH HHS P30 AI078498
6 · The paper itself

Abstract

backgroundUnderstanding the mental health burdens faced by people living with HIV in China is instrumental in the development of successful targeted programs for psychological support and care.

methodsUsing multiple Chinese and English literature databases, we conducted a systematic review of observational research (cross-sectional, case-control, or cohort) published between 1998 and 2014 on the mental health of people living with HIV in China.

resultsWe identified a total of 94 eligible articles. A broad range of instruments were used across studies. Depression was the most widely studied problem; the majority of studies reported prevalence greater than 60% across research settings, with indications of a higher prevalence among women than men. Rates of anxiety tended to be greater than 40%. Findings regarding the rates of suicidality, HIV-related neurocognitive disorders, and substance use were less and varied. Only one study investigated posttraumatic stress disorder and reported a prevalence of 46.2%. Conflicting results about health and treatment related factors of mental health were found across studies.

conclusionsDespite limitations, this review confirmed that people living with HIV are vulnerable to mental health problems, and there is substantial need for mental health services among this population.

Indexed as

Mental HealthAnxiety DisordersChinaDepressionFemaleHIV-1HIV InfectionsHumansMaleNeurocognitive DisordersStress Disorders, Post-TraumaticSuicide

Identifiers

PMID27082749
PMCPMC4833336

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.