ArticleClinical cardiology2016
Age, Gender, and Race-Based Coronary Artery Calcium Score Percentiles in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
Article in Clinical cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022Guideline
- The association between hyperuricemia and coronary artery calcification development: A systematic review and meta-analysis.Clinical cardiology · 2019Pooled it
- Higher exercise capacity, but not omega-3 fatty acid consumption, predicts lower coronary artery calcium scores in women and men with coronary artery disease.Atherosclerosis · 2023Trial
- Association of Coronary Artery Calcium Score with Cardiovascular Outcomes in Patients Without Known Coronary Artery Disease.Life (Basel, Switzerland) · 2026Article
- Evaluation of coronary artery calcium score by age and sex: a multicenter study.The international journal of cardiovascular imaging · 2025Article
- Distribution of coronary artery calcium in a large European all-comer population referred for cardiac imaging.International journal of cardiology. Heart & vasculature · 2025Article
- A machine learning approach to predict positive coronary artery calcium scores in individuals with diabetes: a cross-sectional analysis of ELSA-Brasil baseline data.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Article
- The value of coronary calcium score in predicting clinical outcomes in patients with chronic coronary syndrome.BMC cardiovascular disorders · 2024Article
- Cardiovascular Statistics - Brazil 2023.Arquivos brasileiros de cardiologia · 2024Article
- Coronary artery calcium score percentiles: data from a single center in Turkey.Diagnostic and interventional radiology (Ankara, Turkey) · 2024Article
- The impact of diabetes and subclinical hypothyroidism association with coronary artery calcium: results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).Archives of endocrinology and metabolism · 2023Article
- Determining Percentiles of Atherosclerotic Cardiovascular Risk According to Sex and Age in a Healthy Brazilian Population.Arquivos brasileiros de cardiologia · 2023Article
- Ischemic stroke caused by large-artery atherosclerosis: a red flag for subclinical coronary artery disease.Frontiers in neurology · 2023Article
- Distribution of Coronary Artery Calcium by Age, Sex, and Race Among Patients 30-45 Years Old.Journal of the American College of Cardiology · 2022Article
- Chronic inflammatory diseases, subclinical atherosclerosis, and cardiovascular diseases: Design, objectives, and baseline characteristics of a prospective case-cohort study ‒ ELSA-Brasil.Clinics (Sao Paulo, Brazil) · 2022Article
- Distributions and burden of coronary calcium in asymptomatic Saudi patients referred to computed tomography.International journal of cardiology. Heart & vasculature · 2021Article
- Dietary patterns associated with subclinical atherosclerosis: a cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) study.Public health nutrition · 2021Article
- Impact of Age and Sex on Subclinical Coronary Atherosclerosis in a Healthy Asian Population.JACC. Asia · 2021Article
- Sex Differences in Coronary Artery Calcium and Long-term CV Mortality.Current cardiology reports · 2020Review
- Time of exposure to night work and carotid atherosclerosis: a structural equation modeling approach using baseline data from ELSA-Brasil.International archives of occupational and environmental health · 2018Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCoronary artery calcium (CAC) has been demonstrated to independently predict the risk of cardiovascular events and all-cause mortality, especially among White populations. Although the population distribution of CAC has been determined for several White populations, the distribution in ethnically admixed groups has not been well established. HYPOTHESIS: The CAC distribution, stratified for age, gender and race, is similar to the previously described distribution in the MESA study.
methodsThe Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) is a prospective cohort study designed to investigate subclinical cardiovascular disease in 6 different centers of Brazil. Similar to previous studies, individuals with self-reported coronary or cerebrovascular disease and those treated for diabetes mellitus were excluded from analysis.
resultsPercentiles of CAC distribution were estimated with nonparametric techniques. The analysis included 3616 individuals (54% female; mean age, 50 years). As expected, CAC prevalence and burden were steadily higher with increasing age, as well as increased in men and in White individuals. Our results revealed that for a given CAC score, the ELSA-derived CAC percentile would be lower in men compared with the Multi-Ethnic Study of Atherosclerosis (MESA) and would be higher in women compared with MESA.
conclusionsIn our sample of the Brazilian population, we observed significant differences in CAC by sex, age, and race. Adjusted for age and sex, low-risk individuals from the Brazilian population present with significantly lower CAC prevalence and burden compared with other low-risk individuals from other worldwide populations. Using US-derived percentiles in Brazilian individuals may lead to overestimating relative CAC burden in men and underestimating relative CAC burden in women.
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