Evidence map›Paper›PMID 27081576›Full record

ArticleJournal of nanomedicine & nanotechnology2016

Engineered Protein Polymer-Gold Nanoparticle Hybrid Materials for Small Molecule Delivery.

Min Dai, J A Frezzo, E Sharma, R Chen, N Singh, C Yuvienco, E Caglar, S Xiao, A Saxena, J K Montclare

Abstract read
In one paragraph

Article in Journal of nanomedicine & nanotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Protein-Engineered Functional Materials.Advanced healthcare materials · 2019
    Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Min DaiDepartment of Chemical and Biomolecular Engineering, NYU Tandon School of Engineering, Brooklyn, New York 11201, USA.
J A FrezzoDepartment of Chemical and Biomolecular Engineering, NYU Tandon School of Engineering, Brooklyn, New York 11201, USA.
E SharmaDepartment of Chemical and Biomolecular Engineering, NYU Tandon School of Engineering, Brooklyn, New York 11201, USA.
R ChenDepartment of Chemical and Biomolecular Engineering, NYU Tandon School of Engineering, Brooklyn, New York 11201, USA.
N SinghDepartment of Chemical and Biomolecular Engineering, NYU Tandon School of Engineering, Brooklyn, New York 11201, USA.
C YuviencoDepartment of Chemical and Biomolecular Engineering, NYU Tandon School of Engineering, Brooklyn, New York 11201, USA.
E CaglarDepartment of Biology, Brooklyn College and Graduate Center, City University of New York, Brooklyn, New York 11210, USA.
S XiaoDepartment of Biology, Brooklyn College and Graduate Center, City University of New York, Brooklyn, New York 11210, USA.
A SaxenaDepartment of Biology, Brooklyn College and Graduate Center, City University of New York, Brooklyn, New York 11210, USA.
J K MontclareDepartment of Chemical and Biomolecular Engineering, NYU Tandon School of Engineering, Brooklyn, New York 11201, USA; Department of Chemistry, New York University, New York, New York 10003, USA; Department of Biochemistry, SUNY Downstate Medical Center, Brooklyn, New York 11203, USA.

Funding

Project-005UL1TR001445 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BREDELLA, MIRIAM ANTOINETTE, HOCHMAN, JUDITH S · 2015 to 2025
$103.5M
Institutional Clinical and Translational Science AwardUL1TR000038 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL · 2012 to 2014
$16.8M
Role of nucleolin in regulating mRNA stability during DNA damage response (DDR)R21CA175794 · NCI · BROOKLYN COLLEGE · PI KLEIMAN, FRIDA E, SAXENA, ANJANA DEEPAK · 2013 to 2014
$365k
NCATS NIH HHS UL1 TR000038NCATS NIH HHS UL1 TR001445NCI NIH HHS R21 CA175794
6 · The paper itself

Abstract

We have fabricated protein polymer-gold nanoparticle (P-GNP) nanocomposites that exhibit enhanced binding and delivery properties of the small hydrophobic molecule drug, curcumin, to the model breast cancer cell line, MCF-7. These hybrid biomaterials are constructed via

Indexed as

Drug deliveryGold nanoparticlesNanocompositesProteins

Identifiers

PMID27081576
PMCPMC4828936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.