ArticleZoological letters2016
Comparative morphology and development of extra-ocular muscles in the lamprey and gnathostomes reveal the ancestral state and developmental patterns of the vertebrate head.
Article in Zoological letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 32 citations in OpenAlex.
- Whole-Mount Acetylcholinesterase Staining Reveals Unique Motor Innervation of the Lamprey Oral Region: With Special Reference to the Evolutionary Origin of the Vertebrate Jaw.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2025Article
- Direct retino-iridal projections and intrinsic iris contraction mediate the pupillary light reflex in early vertebrates.Communications biology · 2024Article
- Interplay between Pitx2 and Pax7 temporally governs specification of extraocular muscle stem cells.PLoS genetics · 2024Article
- Unravelling the functional development of vertebrate pathways controlling gaze.Frontiers in cell and developmental biology · 2023Article
- Overview of Head Muscles with Special Emphasis on Extraocular Muscle Development.Advances in anatomy, embryology, and cell biology · 2023Article
- Generation of knock-in lampreys by CRISPR-Cas9-mediated genome engineering.Scientific reports · 2021Article
- The oblique extraocular muscles in cetaceans: Overall architecture and accessory insertions.Journal of anatomy · 2021Article
- Local retinoic acid signaling directs emergence of the extraocular muscle functional unit.PLoS biology · 2020Article
- The role of the optic tectum for visually evoked orienting and evasive movements.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Aqueous-based tissue clearing in crustaceans.Zoological letters · 2018Article
- The phylum Vertebrata: a case for zoological recognition.Zoological letters · 2018Review
- Morphogenesis of Canine Chiari Malformation and Secondary Syringomyelia: Disorders of Cerebrospinal Fluid Circulation.Frontiers in veterinary science · 2018Review
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7 authors at 3 institutions in 1 country.
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Abstract
The ancestral configuration of the vertebrate head has long been an intriguing topic in comparative morphology and evolutionary biology. One peculiar component of the vertebrate head is the presence of extra-ocular muscles (EOMs), the developmental mechanism and evolution of which remain to be determined. The head mesoderm of elasmobranchs undergoes local epithelialization into three head cavities, precursors of the EOMs. In contrast, in avians, these muscles appear to develop mainly from the mesenchymal head mesoderm. Importantly, in the basal vertebrate lamprey, the head mesoderm does not show overt head cavities or signs of segmental boundaries, and the development of the EOMs is not well described. Furthermore, the disposition of the lamprey EOMs differs from those the rest of vertebrates, in which the morphological pattern of EOMs is strongly conserved. To better understand the evolution and developmental origins of the vertebrate EOMs, we explored the development of the head mesoderm and EOMs of the lamprey in detail. We found that the disposition of lamprey EOM primordia differed from that in gnathostomes, even during the earliest period of development. We also found that three components of the paraxial head mesoderm could be distinguished genetically (premandibular mesoderm: Gsc+/TbxA-; mandibular mesoderm: Gsc-/TbxA-; hyoid mesoderm: Gsc-/TbxA+), indicating that the genetic mechanisms of EOMs are conserved in all vertebrates. We conclude that the tripartite developmental origin of the EOMs is likely to have been possessed by the latest common ancestor of the vertebrates. This ancestor's EOM developmental pattern was also suggested to have resembled more that of the lamprey, and the gnathostome EOMs' disposition is likely to have been established by a secondary modification that took place in the common ancestor of crown gnathostomes.
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