ArticleClinical medicine insights. Case reports2016
Primary Hepatic Osteosarcoma: A Rare Cause of Primary Liver Tumor.
Article in Clinical medicine insights. Case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 8 citations in OpenAlex.
- Case Report: Primary gastric extraskeletal osteosarcoma and literature review.Frontiers in medicine · 2026Article
- Visceral Metastases of Osteosarcoma in the Hepatopancreatobiliary System.Journal of clinical medicine · 2025Article
- Two cases of primary hepatic osteosarcoma misdiagnosed as hepatocellular carcinoma.Quantitative imaging in medicine and surgery · 2025Article
- Primary hepatic osteosarcoma: a case report and literature review.Frontiers in oncology · 2025Article
- Article
- Surgical Resection of the Liver Mass with Impending Rupture: Primary Osteosarcoma of Liver-a Histological Surprise and Literature Review.Indian journal of surgical oncology · 2024Article
- Relapsed primary extraskeletal osteosarcoma of liver: A case report and review of literature.World journal of clinical cases · 2023Article
- Primary Exophytic Extraskeletal Osteosarcoma of the Liver: A Case Report and Literature Review.Risk management and healthcare policy · 2021Article
- Primary Osteosarcoma of the Liver: Case Report and Literature Review.Pathology oncology research : POR · 2020Review
- Risk Factors for Development of Canine and Human Osteosarcoma: A Comparative Review.Veterinary sciences · 2019Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionExtraosseous osteosarcomas are rare, accounting for approximately 4% of all osteosarcomas. A literature review yields very few cases of osteosarcoma primarily arising from the hepatic parenchyma. CASE REPORT: This report describes a case of a man in his 50s with a history of hepatitis C and cirrhosis who presented with 5 days of progressive right upper quadrant pain. Magnetic resonance imaging of the abdomen and pelvis demonstrated a 4.4 cm × 4.8 cm × 4.8 cm right hepatic lobe mass with a large area of necrosis and peripheral enhancement. The subsequent liver biopsy showed few cores of tumor composed of fibroblastic malignant cells producing lace-like osteoid matrix. Osteosarcomatous foci in other parts of the body were excluded by performing extensive physical examination, radiologic imaging, and biopsy. Hence, a primary osteosarcoma was diagnosed. The patient underwent portal vein embolization in preparation for a surgical resection of the right liver lobe. He was admitted six weeks after the embolization for dyspnea and abdominal distension and expired due to abdominal hematoma and pulmonary embolism.
conclusionBased on the rarity, lack of consensus in treatment, and dismal prognosis, extraosseous osteosarcoma should be considered a separate entity from osseous osteosarcoma. More data and research are needed in this rare and understudied malignancy.
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