Evidence map›Paper›PMID 27081155›Full record

ArticleDatabase : the journal of biological databases and curation2016

Extraction of chemical-induced diseases using prior knowledge and textual information.

Ewoud Pons, Benedikt F H Becker, Saber A Akhondi, Zubair Afzal, Erik M van Mulligen, Jan A Kors

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Combining relation extraction with function detection for BEL statement extraction.Database : the journal of biological databases and curation · 2019
    Article
  12. Article
  13. Leveraging prior knowledge for protein-protein interaction extraction with memory network.Database : the journal of biological databases and curation · 2018
    Article
  14. Article
  15. Extracting chemical-protein relations using attention-based neural networks.Database : the journal of biological databases and curation · 2018
    Article
  16. Article
  17. Chemical-induced disease relation extraction via convolutional neural network.Database : the journal of biological databases and curation · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ewoud PonsDepartment of Medical Informatics Department of Radiology, Erasmus University Medical Center, 3000 DR Rotterdam, PO Box 2040, The Netherlands.
Benedikt F H BeckerDepartment of Medical Informatics b.becker@erasmusmc.nl.
Saber A AkhondiDepartment of Medical Informatics.
Zubair AfzalDepartment of Medical Informatics.
Erik M van MulligenDepartment of Medical Informatics.
Jan A KorsDepartment of Medical Informatics.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe our approach to the chemical-disease relation (CDR) task in the BioCreative V challenge. The CDR task consists of two subtasks: automatic disease-named entity recognition and normalization (DNER), and extraction of chemical-induced diseases (CIDs) from Medline abstracts. For the DNER subtask, we used our concept recognition tool Peregrine, in combination with several optimization steps. For the CID subtask, our system, which we named RELigator, was trained on a rich feature set, comprising features derived from a graph database containing prior knowledge about chemicals and diseases, and linguistic and statistical features derived from the abstracts in the CDR training corpus. We describe the systems that were developed and present evaluation results for both subtasks on the CDR test set. For DNER, our Peregrine system reached anF-score of 0.757. For CID, the system achieved anF-score of 0.526, which ranked second among 18 participating teams. Several post-challenge modifications of the systems resulted in substantially improvedF-scores (0.828 for DNER and 0.602 for CID). RELigator is available as a web service athttp://biosemantics.org/index.php/software/religator.

Indexed as

Databases, FactualComputational BiologyData MiningDiseaseHazardous SubstancesHumansToxicogeneticsHazardous Substances

Identifiers

PMID27081155
PMCPMC4831722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.