ArticleReproductive health2016
Investigating paternal preconception risk factors for adverse pregnancy outcomes in a population of internet users.
Article in Reproductive health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- The high-priority ethical issues of advanced paternal age: perspectives from a panel of experts in the fields of men reproduction and family building.BMC medical ethics · 2025Article
- Preconceptional paternal obesity may increase the risk of congenital urogenital anomalies in offspring: A case-control study.Andrology · 2025Article
- Article
- Public Engagement in Digital Recommendations for Promoting Healthy Parental Behaviours from Preconception through the First 1000 Days.International journal of environmental research and public health · 2023Article
- Review
- Article
- The Relationship Between Paternal Preconception Obesity and Health Behaviors and Childhood Obesity: Protocol for a Systematic Review.JMIR research protocols · 2021Article
- Paternal prescription medication before conception: A retrospective cohort study of all births in Denmark 1997-2017.Scandinavian journal of public health · 2021Article
- Paternal characteristics associated with low birth weight among singleton births: a hospital-based birth cohort study in northern Tanzania.The Pan African medical journal · 2021Article
- Defining preconception: exploring the concept of a preconception population.BMC pregnancy and childbirth · 2020Review
- The forgotten father in obstetric medicine.Obstetric medicine · 2019Review
- Preparation for fatherhood: A survey of men's preconception health knowledge and behaviour in England.PloS one · 2019Article
- It's the mother!: How assumptions about the causal primacy of maternal effects influence research on the developmental origins of health and disease.Social science & medicine (1982) · 2018Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPaternal preconception risk factors such as smoking, exposure to environmental substances, medication use, overweight and advanced age correlate with the occurrence of malformations and birth defects in the offspring. Nonetheless, the prevalence of risk factors for adverse pregnancy outcomes in the male population has been scarcely investigated and no report on preconception interventions targeting prospective fathers is available. We conducted a web-based survey to measure the prevalence of paternal preconception risk factors for adverse pregnancy outcomes in an Italian population of Internet users.
methodsProspective or expectant fathers were enrolled during a four-week period through two of the main Italian web-sites dedicated to preconception, pregnancy, childhood and family care. Participants filled in a web questionnaire regarding preconception risk factors for adverse pregnancy outcomes. Logistic regression analysis was used to explore the predictors of paternal preconception risk factors.
resultsWe enrolled 131 prospective and 205 expectant fathers. More than half of the total participants used medications during the preconception period, 35% were smokers and 8% were obese. Exposure to environmental substances was declared by almost 20% of the participants, with the group including pesticides/herbicides/professional paints being the most prevalent. More than a half of the study sample included men aged over 35 years. According to the multivariate analysis, smoking and exposure to environmental toxics were less frequent among individuals with a university degree (respectively: OR = 0.52; 95% CI 0.32-0.84; OR = 0.52; 95% CI 0.29-0.93). Paternal obesity and medication use in the preconception period were not associated with any of the independent variables.
conclusionsThe prevalence of preconception risk factors among male population should not be neglected when planning preconception interventions, confirming that preconception health must be focused on the couple, rather than on women only.
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