Evidence map›Paper›PMID 27079581›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2016

Symptom clusters in patients with cancer in the hospice/palliative care setting.

Stephen J Stapleton, Janean Holden, Joel Epstein, Diana J Wilkie

Abstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
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  9. Cumulative Burden of Morbidity Among Testicular Cancer Survivors After Standard Cisplatin-Based Chemotherapy: A Multi-Institutional Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018
    Article
  10. Palliative care needs in hospitalized cancer patients: a 5-year follow-up study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  11. An update in symptom clusters using the Edmonton Symptom Assessment System in a palliative radiotherapy clinic.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Article
  12. Article
  13. Symptom clusters during palliative chemotherapy and their influence on functioning and quality of life.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephen J StapletonMennonite College of Nursing, Illinois State University, 210 Edwards Hall, Campus Box 5810, Normal, IL, 61790, USA. sstaple@ilstu.edu.
Janean HoldenSchool of Nursing, University of Michigan, 400 North Ingalls Building, Ann Arbor, MI, 48109-5482, USA.
Joel EpsteinSamuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Diana J WilkieDepartment of Biobehavioral Nursing Science, College of Nursing, University of Florida, 1225 Center Drive, Room 2203, Gainesville, FL, 32610, USA.

Funding

Nursing and Health Research Informatics CoreP30NR010680 · NINR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FOREMAN, MARQUIS D · 2007 to 2011
$2.4M
Effects &Costs of Massage in Hospice Cancer PatientsR01NR009092 · NINR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WILKIE, DIANA J · 2005 to 2009
$1.8M
Symptom Clusters in the Palliative Care SettingF31NR010048 · NINR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI STAPLETON, STEPHEN JAMES · 2007 to 2009
$57k
NINR NIH HHS F31 NR010048NINR NIH HHS P30 NR010680NINR NIH HHS R01 NR009092
6 · The paper itself

Abstract

purposeWe determined commonly experienced symptoms reported by adult patients with cancer admitted to urban, ethnically diverse hospice settings and identified symptom clusters.

methodsWe used hierarchical cluster analysis of 150 patients (41 % male, 20-92 years [M = 59, SD = 13.3], 51 % African American, 37 % Caucasian, 12 % other). Using pen-tablet computers, participants completed the Symptom Distress Scale (SDS), a sleep quality item, and listed analgesics consumed in the previous 24 h.

resultsFour symptom clusters were identified: cluster 1 (Pain-Fatigue) consisted of pain frequency, fatigue, and pain intensity; cluster 2 (Ingestion-Elimination) consisted of appetite and bowel problems; cluster 3 (General Well-Being) consisted of insomnia, appearance, and outlook; and cluster 4 (Respiratory-Nausea-Concentration) consisting of breathing, cough, nausea frequency, nausea intensity, and concentration. There were no significant differences between Caucasians and African Americans on total SDS scores, analgesic consumption, sleep quality, or most cluster scores.

conclusionThis is the first symptom cluster analysis in a US sample with a sizeable proportion of minority hospice/palliative care patients with cancer. Further research to determine the stability of identified symptom clusters over time and discovery of the biological interactions of symptoms within the cluster may lead to symptom management therapies designed for the alleviation of all clustered symptoms.

Indexed as

AdultAgedAged, 80 and overFemaleHospicesHumansMaleMiddle AgedNeoplasmsPalliative CareYoung AdultCancerHierarchical cluster analysisHospicePalliative carePittsburgh sleep quality indexSymptom clustersSymptom distress scale

Identifiers

PMID27079581
PMCPMC4967396

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.