Evidence map›Paper›PMID 27077574›Full record

Trial reportThe journal of spinal cord medicine2016

Longitudinal changes in body composition and metabolic profile between exercise clinical trials in men with chronic spinal cord injury.

Ashraf S Gorgey, Heather Martin, Alyse Metz, Refka E Khalil, David R Dolbow, David R Gater

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The journal of spinal cord medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  20. Energy Expenditure Following Spinal Cord Injury: A Delicate Balance.Topics in spinal cord injury rehabilitation · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ashraf S Gorgeya Spinal Cord Injury Service and Disorders, Hunter Holmes McGuire VA Medical Center , Richmond , VA , USA.
Heather Martina Spinal Cord Injury Service and Disorders, Hunter Holmes McGuire VA Medical Center , Richmond , VA , USA.
Alyse Metza Spinal Cord Injury Service and Disorders, Hunter Holmes McGuire VA Medical Center , Richmond , VA , USA.
Refka E Khalila Spinal Cord Injury Service and Disorders, Hunter Holmes McGuire VA Medical Center , Richmond , VA , USA.
David R Dolbowd School of Kinesiology, College of Health, University of Southern Mississippi , Hattiesburg , MS , USA.
David R Gatere Department of Physical Medicine and Rehabilitation , Penn State Milton S. Hershey Medical Center , Hershey , PA , USA.

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR031990 · NCRR · VIRGINIA COMMONWEALTH UNIVERSITY · PI CLORE, JOHN N. · 2010 to 2011
$7.7M
NCRR NIH HHS UL1 RR031990
6 · The paper itself

Abstract

STUDY

designLongitudinal design.

objectivesThe study was undertaken to determine the effects of cessation of exercise interventions on body composition and metabolic profiles in men with chronic SCI. SETTINGS: Clinical trials within a Medical Center.

methodsEleven men with motor complete SCI were followed on average over a period of 2.5 years. Six men were involved in two different exercise interventions (functional electrical stimulation cycling versus arm cycling ergometer), 5 days/week for 16 weeks (exercise group), and five men served as a control (control group). Anthropometrics and dual energy X-ray absorptiometry (DXA) were captured to measure changes in lean mass (LM), fat mass (FM), percentage FM before, immediately after exercise, and after a period of 2.5 years. Basal metabolic rate (BMR) and lipid panel were also measured.

resultsThigh circumference increased by 8.5% following exercise (P = 0.042) and remained 6.4% greater than baseline measurements (P = 0.012). Leg LM increased by 9% following the exercise intervention (P = 0.03) and decreased by 16% in the follow-up visit (P = 0.02). Percentage trunk and total body FM increased by 4.5% (P = 0.008) and 3.5% (P = 0.019) in the follow-up visit, respectively, and whole body LM increased by 8.4% and decreased back by 5.4% following a 2.5 year-period. BMR significantly decreased by 15.5% following the exercise (P = 0.029) interventions.

conclusionExercise training is accompanied with positive changes in body composition as well as compensatory decrease in BMR, that regressed back following 2.5 years of exercise cessation. Participation in an exercise trial is unlikely to confound the measurements of a follow-up trial.

Indexed as

Body CompositionMetabolomeAdultBasal MetabolismElectric Stimulation TherapyExercise TherapyHumansMaleSpinal Cord InjuriesArm-crank ergometerBody compositionClinical trialsExerciseFunctional electrical stimulationMetabolic profileSpinal cord injury

Identifiers

PMID27077574
PMCPMC5137575

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.