ArticleJournal of thoracic disease2016
Dysphagia, dystussia, and aspiration pneumonia in elderly people.
Article in Journal of thoracic disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
67 citing papers in PubMed, 1 synthesis or guideline pooled it, 161 citations in OpenAlex.
- Computer-aided screening of aspiration risks in dysphagia with wearable technology: a Systematic Review and meta-analysis on test accuracy.Frontiers in bioengineering and biotechnology · 2023Pooled it
- Effectiveness of Cleaning Methods for Resilient Denture Liners: A Three-Period Randomized Crossover Trial.Clinical and experimental dental research · 2025Trial
- Trial
- Dysphagia in hospitalized older patients: the Report-AGE project.European geriatric medicine · 2026Observational
- Review
- Automatic measurement of pharyngeal contraction ratio during deglutition using 2D cine MRI with deep learning: A pilot study.Radiological physics and technology · 2026Article
- Association Between Pneumonia Risk and Anticholinergic Burden Among Patients with Different Frailty Levels [Response to Letter].Clinical epidemiology · 2026Article
- Review
- Frailty, periinterventional complications and outcome in patients undergoing percutaneous mitral and tricuspid valve repair.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Anticholinergic drug exposure is associated with prevalence, worsening and incidence of dysphagia among hospitalized older adults.The journal of nutrition, health & aging · 2025Article
- AI-boosted and motion-corrected, wireless near-infrared sensing system for continuously monitoring laryngeal muscles.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A Pilot Study to Assess the Feasibility of Real-Time Teledentistry in Residential Aged Care Facilities.Healthcare (Basel, Switzerland) · 2024Article
- Article
- Adverse postoperative outcomes in elderly patients with sarcopenia.BMC geriatrics · 2024Article
- The relationship between oral frailty and oral dysbiosis among hospitalized patients aged older than 50 years.Clinical and experimental dental research · 2024Observational
- A simple nomogram for predicting aspiration associated with dysphagia in hospitalized patients after stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Differences in cough strength, respiratory function, and physical performance in older adults with and without low swallowing function in the repetitive saliva swallowing test.Journal of physical therapy science · 2024Article
- Hypotussic cough in persons with dysphagia: biobehavioral interventions and pathways to clinical implementation.Frontiers in rehabilitation sciences · 2024Review
- Article
- Transient receptor potential channels as an emerging therapeutic target for oropharyngeal dysphagia.The Japanese dental science review · 2023Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the development and wide distribution of guidelines for pneumonia, death from pneumonia is increasing due to population aging. Conventionally, aspiration pneumonia was mainly thought to be one of the infectious diseases. However, we have proven that chronic repeated aspiration of a small amount of sterile material can cause the usual type of aspiration pneumonia in mouse lung. Moreover, chronic repeated aspiration of small amounts induced chronic inflammation in both frail elderly people and mouse lung. These observations suggest the need for a paradigm shift of the treatment for pneumonia in the elderly. Since aspiration pneumonia is fundamentally based on dysphagia, we should shift the therapy for aspiration pneumonia from pathogen-oriented therapy to function-oriented therapy. Function-oriented therapy in aspiration pneumonia means therapy focusing on slowing or reversing the functional decline that occurs as part of the aging process, such as "dementia → dysphagia → dystussia → atussia → silent aspiration". Atussia is ultimate dysfunction of cough physiology, and aspiration with atussia is called silent aspiration, which leads to the development of life-threatening aspiration pneumonia. Research pursuing effective strategies to restore function in the elderly is warranted in order to decrease pneumonia deaths in elderly people.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.