Evidence map›Paper›PMID 27076527›Full record

ArticleAge and ageing2016

Late-life deficits in cognitive, physical and emotional functions, childhood intelligence and occupational profile: a life-course examination of the Aberdeen 1936 Birth Cohort (ABC1936).

Dorota Chapko, Roger T Staff, Christopher J McNeil, Lawrence J Whalley, Corri Black, Alison D Murray

Abstract read
In one paragraph

Article in Age and ageing, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dorota ChapkoAberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK.
Roger T StaffNuclear Medicine, Aberdeen Royal Infirmary NHS-Grampian, Aberdeen, UK.
Christopher J McNeilAberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK.
Lawrence J WhalleyAberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK.
Corri BlackFarr Institute@Scotland, Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
Alison D MurrayAberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK.

Funding

Arthritis Research UKBiotechnology and Biological Sciences Research CouncilBritish Heart FoundationCancer Research UKChief Scientist OfficeMedical Research Council MR/K007017/1Wellcome Trust
6 · The paper itself

Abstract

objectivesthe 'triad of impairment' phenomenon describes the co-occurrence of age-related cognitive, emotional and physical functioning deficits. We investigated how occupational profile and childhood intelligence contribute to the triad of impairment in late life.

methodswe analysed data of a subsample of the Aberdeen Birth Cohort of 1936 (n = 346). Data were collected on participants' childhood intelligence, late-life cognitive ability, physical functioning, depressive symptoms and main lifetime occupation. We summarised the various occupational and impairment measures into two latent variables, 'occupational profile' and the 'triad of impairment'. We used a series of data reduction approaches and structural equation models (SEMs) of increasing complexity to test both the validity of the models and to understand causal relationships between the life-course risks for the triad of impairment.

resultsoccupational profile had a significant effect on the triad of impairment independent of childhood intelligence. Childhood intelligence was the predominant influence on the triad of impairment and exerted its effect directly and indirectly via its influence on occupation. The direct effect of childhood intelligence exceeded the independent influence of the occupational profile on impairment by a factor of 1.7-1.8 and was greater by a factor of ∼4 from the indirect pathway (via occupation).

conclusionschildhood intelligence was the predominant influence on the triad of impairment in late life, independently of the occupational profile. Efforts to reduce impairment in older adults should be informed by a life-course approach with special attention to the early-life environment.

Indexed as

Child DevelopmentCognitionEmotionsHealth StatusIntelligenceOccupationsAgedAge FactorsChildCognition DisordersCognitive AgingDepressionFemaleHumansMaleMiddle Agedchildhood IQcognitive impairmentdepressive symptomsoccupationolder peoplephysical functioning

Identifiers

PMID27076527
PMCPMC4916342

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.