Evidence map›Paper›PMID 27076186›Full record

ArticleAnnals of intensive care2016

Treatment intensity and outcome of nonagenarians selected for admission in ICUs: a multicenter study of the Outcomerea Research Group.

Maité Garrouste-Orgeas, Stéphane Ruckly, Charles Grégoire, Anne-Sylvie Dumesnil, Cécile Pommier, Samir Jamali, Dany Golgran-Toledano, Carole Schwebel, Christophe Clec'h, Lilia Soufir and 7 more

Open access · goldAbstract read
In one paragraph

Article in Annals of intensive care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Selection and Receipt of Kidney Replacement in Critically Ill Older Patients with AKI.Clinical journal of the American Society of Nephrology : CJASN · 2019
    Article
  12. Article
  13. The golden hour of acute ischemic stroke.Scandinavian journal of trauma, resuscitation and emergency medicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 1 country.

Maité Garrouste-OrgeasService de Réanimation et de médecine intensive, Medical-Surgical ICU, Saint Joseph Hospital Network, 185 rue Raymond Losserand, 75014, Paris, France. mgarrouste@hpsj.fr.
Stéphane RucklyDepartment of Biostatistics, Outcomerea, Paris, France.
Charles GrégoireService de Réanimation et de médecine intensive, Medical-Surgical ICU, Saint Joseph Hospital Network, 185 rue Raymond Losserand, 75014, Paris, France.
Anne-Sylvie DumesnilMedical-Surgical ICU, AP-HP, Antoine Béclère University Hospital, Clamart, France.
Cécile PommierDepartment of Biostatistics, Outcomerea, Paris, France.
Samir JamaliMedical-Surgical, General Hospital, Dourdan, France.
Dany Golgran-ToledanoMedical-Surgical ICU, General Hospital, Montfermeil, France.
Carole SchwebelMedical ICU, Albert Michallon University Hospital, Grenoble, France.
Christophe Clec'hMedical-Surgical ICU, AP-HP, Avicennes University Hospital, Bobigny, France.
Lilia SoufirService de Réanimation et de médecine intensive, Medical-Surgical ICU, Saint Joseph Hospital Network, 185 rue Raymond Losserand, 75014, Paris, France.
Muriel FartoukhMedical ICU, AP-HP, Tenon University Hospital, Paris, France.
Guillaume MarcotteMedical-Surgical ICU, Hospices civils de Lyon, Hôpital Edouard Herriot, Lyon, France.
Laurent ArgaudMedical ICU, Hospices civils de Lyon, Hôpital Edouard Herriot, Lyon, France.
Bruno VerdièreMedical-Surgical ICU, Delafontaine University Hospital, Saint Denis, France.
Michael DarmonMedical-Surgical ICU, Saint Etienne University Hospital, Saint Priest en Jarez, France.
Elie AzoulayMedical ICU, AP-HP, Saint Louis University Hospital, Paris, France.
Jean-François TimsitInfection, Antimicrobials, Modelling, Evolution (IAME), UMR 1137, INSERM and Paris Diderot University, Department of Biostatistics - HUPNVS. - AP-HP, UFR de Médecine, Bichat University Hospital, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRHôpital Edouard Herriot · FRCentre Hospitalier Saint-Denis · FRDélégation Paris 7 · FRGroupe Hospitalier Intercommunal Le Raincy Montfermeil · FRHôpital Albert Michallon · FRInstitute Cancer De La Loire Lucien Neuwirth · FRUniversité Sorbonne Paris Nord · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOutcome of very elderly patients admitted in intensive care unit (ICU) was most often reported for octogenarians. ICU admission demands for nonagenarians are increasing. The primary objective was to compare outcome and intensity of treatment of octogenarians and nonagenarians.

methodsWe performed an observational study in 12 ICUs of the Outcomerea™ network which prospectively upload data into the Outcomerea™ database. Patients >90 years old (case patients) were matched with patients 80-90 years old (control patients). Matching criteria were severity of illness at admission, center, and year of admission.

resultsA total of 2419 patients aged 80 or older and admitted from September 1997 to September 2013 were included. Among them, 179 (7.9 %) were >90 years old. Matching was performed for 176 nonagenarian patients. Compared with control patients, case patients were more often hospitalized for unscheduled surgery [54 (30.7 %) vs. 42 (23.9 %), p < 0.01] and had less often arterial monitoring for blood pressure [37 (21 %) vs. 53 (30.1 %), p = 0.04] and renal replacement therapy [5 (2.8 %) vs. 14 (8 %), p = 0.05] than control patients. ICU [44 (25 %) vs. 36 (20.5 %), p = 0.28] or hospital mortality [70 (39.8 %) vs. 64 (36.4 %), p = 0.46] and limitation of life-sustaining therapies were not significantly different in case versus control patients, respectively. Only 16/176 (14 %) of case patients were transferred to a geriatric unit.

conclusionThis multicenter study reported that nonagenarians represented a small fraction of ICU patients. When admitted, these highly selected patients received similar life-sustaining treatments, except RRT, than octogenarians. ICU and hospital mortality were similar between the two groups.

Indexed as

80 and overElderlyEnd of lifeIntensive care unitTriage

Identifiers

PMID27076186
PMCPMC4830777
OpenAlexW2342204152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.