Evidence map›Paper›PMID 27076071›Full record

ArticleCell metabolism2016

VEGF-B Improves Metabolic Health through Vascular Pruning of Fat.

Shahin Rafii, Peter Carmeliet

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Shahin RafiiDivision of Regenerative Medicine, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: srafii@med.cornell.edu.
Peter CarmelietLaboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Centre (VRC), 3000 Leuven, Belgium. Electronic address: peter.carmeliet@vib-kuleuven.be.
Cornell University · USVIB-KU Leuven Center for Cancer Biology · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unraveling the mechanism VEGF-receptors modulating metabolism has therapeutic implications. In this issue, Robciuc et al. (2016) demonstrate that VEGF-B, by displacing VEGF-A from VEGFR1 and activating VEGFR2, increases adipose tissue vascularity, improves insulin sensitivity, diminishes obesity, and alleviates metabolic syndrome.

Indexed as

Vascular Endothelial Growth Factor BHumansInsulin ResistanceObesityVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-2Vascular Endothelial Growth Factor AVascular Endothelial Growth Factor BVascular Endothelial Growth Factor Receptor-2

Identifiers

PMID27076071
OpenAlexW2341447171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.