ArticleEndocrine2017
Surgical treatment of thyroid follicular neoplasms: results of a retrospective analysis of a large clinical series.
Article in Endocrine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 57 citations in OpenAlex.
- Pathology-based thermal ablation safety margin for follicular adenoma: a digital whole-slide study of follicular carcinoma invasion.Frontiers in endocrinology · 2026Article
- Patient-specific factors, patient preference, and nodule size as implications in the initial surgery of high risk indeterminate thyroid nodules.Endocrine · 2025Article
- Proteomics analysis reveals elevated RAB21 in serum-derived extracellular vesicles from patients with follicular thyroid carcinoma.Oncology letters · 2025Article
- Efficacy, safety, and risk factors of thermal ablation for follicular thyroid neoplasms: a multicentric study.Endocrine · 2025Article
- Role of clinicopathologic and sonographic characteristics for the management of patients with cytological diagnosis of thyroid follicular neoplasm.Gland surgery · 2024Article
- Diagnostic significance of ultrasound characteristics in discriminating follicular thyroid carcinoma from adenoma.BMC medical imaging · 2024Article
- Evolutionary analysis of indeterminate cytology and risk of malignancy in a thyroid nodule unit.European thyroid journal · 2024Article
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- Thyroidectomy with energy-based devices: surgical outcomes and complications-comparison between Harmonic Focus, LigaSure Small Jaw and Thunderbeat Open Fine Jaw.Gland surgery · 2020Article
- Effect of prophylactic central neck dissection on the surgical outcomes in papillary thyroid cancer: experience in a single center.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Article
- Impact of the Italian Society of Anatomic Pathology and Diagnostic Cytology Classification of Thyroid Nodules in the Treatment of Indeterminate Follicular Lesions: Five-Year Results at a Single Center.International journal of endocrinology · 2020Article
- Preoperative ultrasound evaluation of laterocervical lymph nodes: timing and experience modify the treatment of patients with differentiated thyroid cancer.Updates in surgery · 2019Article
- Identification and interaction analysis of key miRNAs in medullary thyroid carcinoma by bioinformatics analysis.Molecular medicine reports · 2019Article
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- The role of prophylactic central compartment lymph node dissection in elderly patients with differentiated thyroid cancer: a multicentric study.BMC surgery · 2019Article
- Thyroiditis process as a predictive factor of sternotomy in the treatment of cervico-mediastinal goiter.BMC surgery · 2019Article
- Correlation between iPTH Levels on the First Postoperative Day After Total Thyroidectomy and Permanent Hypoparathyroidism: Our Experience.Open medicine (Warsaw, Poland) · 2019Article
- Prevalence of hypothyroidism among patients with isthmus-preserved thyroid lobectomy.The Journal of international medical research · 2018Article
- How to handle borderline/precursor thyroid tumors in management of patients with thyroid nodules.Gland surgery · 2018Review
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Authors and funding
22 authors at 14 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most appropriate surgical management of "follicular neoplasm/suspicious for follicular neoplasm" lesions (FN), considering their low definitive malignancy rate and the limited predictive power of preoperative clinic-diagnostic factors, is still controversial. On behalf of the Italian Association of Endocrine Surgery Units (U.E.C. CLUB), we collected and analyzed the experience of 26 endocrine centers by computerized questionnaire. 1379 patients, surgically treated after a FN diagnosis from January 2012 and December 2103, were evaluated. Histological features, surgical complications, and medium-term outcomes were reported. Total thyroidectomy (TT) was performed in 1055/1379 patients (76.5 %), while hemithyroidectomy (HT) was carried out in 324/1379 cases (23.5 %). Malignancy rate was higher in TT than in HT groups (36.4 vs. 26.2 %), whereas the rates of transient and definitive hypoparathyroidism following TT were higher than after HT. Consensual thyroiditis (16.8 vs. 9.9 %) and patient age (50.9 vs. 47.9 %) also differed between groups. A cytological FN diagnosis was associated to a not negligible malignancy rate (469/1379 patients; 34 %), that was higher in TT than in HT groups. However, a lower morbidity rate was observed in HT, which should be considered the standard of care in solitary lesions in absence of specific risk factors. Malignancy could not be preoperatively assessed and clinical decision-making is still controversial. Further efforts should be spent to more accurately preoperatively classify FN thyroid nodules.
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