ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2017
Low serum albumin may predict the need for gastric resection in patients with perforated peptic ulcer.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 20 citations in OpenAlex.
- Predicting in-hospital mortality risk for perforated peptic ulcer surgery: the PPUMS scoring system and the benefit of laparoscopic surgery: a population-based study.Surgical endoscopy · 2023Article
- Omental patch repair of large perforated peptic ulcers ≥25 mm is associated with higher leak rate.Journal of clinical and translational research · 2021Article
- Outcomes of omental patch repair in large or giant perforated peptic ulcer are comparable to gastrectomy.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021Article
- Low serum albumin may predict poor efficacy in patients with perforated peptic ulcer treated nonoperatively.World journal of gastrointestinal surgery · 2021Article
- Marginal ulcer perforation: a single center experience.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2017Article
- Focus on acute care surgery.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2017Article
- Perforated peptic ulcer - an update.World journal of gastrointestinal surgery · 2017Review
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Authors and funding
3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposePerforated peptic ulcer (PPU) is a common surgical emergency and treatment involves omental patch repair (PR). Gastric resection (GR) is reserved for difficult pathologies. We audit the outcomes of GR at our institution and evaluate the pre-operative factors predicting the need for GR.
methodsThis is a single-institution, retrospective study of patients with PPU who underwent surgery from 2004 to 2012. Demographics, clinical presentation and intra-operative findings were studied to identify factors predicting the need for GR in PPU. An audit of clinical outcomes and mortality for all patients with GR is reported.
results537 (89.6 %) patients underwent PR and 62 (10.4 %) patients GR. Old age (p < 0.0001), female sex (p = 0.0123), non-steroidal anti-inflammatory drugs (NSAIDs) usage (p = 0.0008), previous history of peptic ulcer disease (PUD) (p = 0.0159), low hemoglobin (p < 0.0001), low serum albumin (p < 0.0001), high serum creatinine (p = 0.0030), high urea (p = 0.0006) and large ulcer size (p < 0.0001) predict the need for GR. On multivariate analysis only low serum albumin (OR 5.57, 95 % CI 1.56-19.84, p = 0.008) predicted the need for GR. The presence of Helicobacter pylori infection was protective against GR (OR 0.25, 95 %CI 0.14-0.44, p < 0.0001). Morbidity and mortality of GR was 27.7 and 24.2 %, respectively.
conclusionGR is needed in one in ten cases of PPU. Low serum albumin predicted the need for GR on multivariate analysis. Morbidity and mortality of GR remains high.
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